[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552361":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":35,"locations":43,"responsibleParty":93,"collaborators":96,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":9,"eligibilityCriteria":106,"healthyVolunteers":102,"sex":107,"minAge":108,"maxAge":25,"enrollmentInfo":109,"targetDuration":25,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BMT-CARE","EXPERIMENTAL","Participants randomized to BMT-CARE plus usual care will complete the following:\n\n* Questionnaires at baseline, and days 60, 90 and 180 post HCT.\n* Receive the BMT-CARE intervention from enrollment up to 60 days post-HCT. BMT-CARE is a -6-session caregiver-directed cognitive behavioral therapy (CBT)-based psychosocial intervention that integrates HCT-related education with CBT strategies to enhance caregiver knowledge and skills.\n* Receive usual care as per HCT practice which entails meeting a transplant social worker prior to HCT and as needed for extra visits.",[13],"Behavioral: BMT-CARE",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","ACTIVE_COMPARATOR","Participants randomized to usual care will complete the following\n\n* Questionnaires at baseline, and days 60, 90 and 180 post HCT.\n* Receive usual care as per HCT practice which entails meeting a transplant social worker prior to HCT and as needed for extra visits.",[19],"Behavioral: Usual Care",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Therapist-delivered psychosocial intervention comprised of 6 sessions",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Meeting a transplant social worker prior to HCT and as needed for extra visits",[15],[30,33],{"name":31,"affiliation":5,"role":32},"Areej El-Jawahri, MD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Jamie Jacobs, PhD",[36,40],{"name":31,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","617-721-4000","ael-jawahri@mgb.org",{"name":34,"role":37,"phone":41,"phoneExt":25,"email":42},"617-724-4000","jjacobs@mgh.harvard.edu",[44,63,78],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"University of Alabama at Brimingham","RECRUITING","Birmingham","Alabama","35294","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-86.80249,33.52066,{"lat":56,"lon":55},[59],{"name":60,"role":37,"phone":61,"phoneExt":25,"email":62},"James Dionne-Odom","205-934-7597","dionneod@uab.edu",{"facility":64,"status":46,"city":65,"state":66,"zip":67,"country":50,"countryCode":51,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Moffitt Cancer Center","Tampa","Florida","33612",{"type":53,"coordinates":69},[70,71],-82.45843,27.94752,{"lat":71,"lon":70},[74],{"name":75,"role":37,"phone":76,"phoneExt":25,"email":77},"Heather Jim","813-745-6369","heather.jim@moffitt.org",{"facility":79,"status":46,"city":80,"state":81,"zip":82,"country":50,"countryCode":51,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"Massachusetts General Hospital Cancer Center","Boston","Massachusetts","02114",{"type":53,"coordinates":84},[85,86],-71.05977,42.35843,{"lat":86,"lon":85},[89,92],{"name":31,"role":37,"phone":90,"phoneExt":25,"email":91},"617-643-4003","AEL-JAWAHRI@PARTNERS.ORG",{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"type":32,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"El-Jawahri, Areej,M.D.","Associate Professor of Medicine",[97],{"name":98,"class":99},"National Institutes of Health (NIH)","NIH","100552361","bmt-care-psychosocial-intervention-for-transplant-caregivers-100552361",false,"NCT06472089","BMT-CARE: Psychosocial Intervention for Transplant Caregivers","Multimodal Psychosocial Intervention for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation","Caregiver Inclusion Criteria:\n\n* Adult caregivers (≥18 years) relative or friend of a patient identified as living with them or having in-person contact with them at least twice a week.\n* Caregiver of a patient receiving allogeneic or autologous HCT for the treatment of cancer.\n* Ability to read and respond to survey questions in English, Spanish or with minimal assistance from an interpreter.\n\nCaregiver Exclusion Criteria:\n\n* Caregivers of patients undergoing HCT for a benign hematologic condition or undergoing outpatient HCT.\n* Caregivers with a major untreated psychiatric or cognitive condition which the treating oncology clinicians believes interferes with the capacity to provide informed consent.\n* Caregivers of patients who have already undergone HCT within the past 5 years\n\nPatient Inclusion Criteria:\n\n* Adult patients (≥18 years) with a hematologic malignancy and planned admission for autologous or allogeneic HCT.\n* Ability to respond to questions in English, Spanish, or with minimal assistance from an interpreter.","ALL","18 Years",{"count":110,"type":111},800,"ESTIMATED","INTERVENTIONAL",[114],"NA","The goal of this study is to evaluate whether a psychological intervention (BMT-CARE) is effective at improving the quality of life in caregivers and patients treated with hematopoietic cell transplant compared to usual care, and to identify critical facilitators and barriers for BMT-CARE implementation and adoption.",[117,118],"Bone Marrow Transplant Complications","Hematologic Malignancy",[120,121,122,123],"Neoplasms by Site","Hematologic Diseases","Neoplasms","Hematologic Neoplasms","2025-10-13",{"date":126,"type":127},"2025-10-15","ACTUAL",{"date":129,"type":127},"2025-01-10",{"date":131,"type":111},"2029-02",{"name":5,"class":6},3]