[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100417291":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":25,"responsibleParty":44,"collaborators":7,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":7,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":7,"enrollmentInfo":55,"targetDuration":7,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":7,"overallStatus":28,"whyStopped":7,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"University of Liege","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","High-resolution peripheral quantitative CT scanner (HRpQCT)","HR-pQCT images of the distal radius and distal tibia (non-dominant, non-fractured limb) will be obtained using the XtremeCT device with standard protocols. HR-pQCT images wil be analysed with standard software and extended cortical measures software. This software identifies the periosteal and endosteal boundaries, enabling assessment of cortical micro- structural bone properties, including apparent cortical thickness (Ct.Th, mm), cortical tissue mineral density (TMD, mgHA\u002Fcm3) and cortical porosity (Ct.Po, %).",[14],{"name":15,"affiliation":5,"role":16},"Antoine Bouquegneau","PRINCIPAL_INVESTIGATOR",[18,22],{"name":15,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","+32473353321","antoine.bouquegneau@gmail.com",{"name":23,"role":19,"phone":7,"phoneExt":7,"email":24},"Pierre Delanaye","pierre_delanaye@yahoo.fr",[26],{"facility":27,"status":28,"city":29,"state":7,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Centre Hospitalier Universitaire de Liège","RECRUITING","Liège","4300","Belgium","BE",{"type":34,"coordinates":35},"Point",[36,37],5.56749,50.63373,{"lat":37,"lon":36},[40,43],{"name":41,"role":19,"phone":42,"phoneExt":7,"email":21},"Antoine Bouquegneau, MD","0032473353321",{"name":23,"role":19,"phone":7,"phoneExt":7,"email":7},{"type":16,"investigatorFullName":15,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Principal Investigator","100417291","bone-density-and-vascular-calcifications-evolution-after-renal-transplant-100417291",false,"NCT04713774","Bone Density and Vascular Calcifications Evolution After Renal Transplant","Evolution of Bone Density, Bone Micro-architecture and Vascular Calcifications in Patients After Kidney Transplantation","Inclusion Criteria:\n\n* At least 18 years old\n* Recent kidney transplant patients (\\\u003C3 months)\n* Medical history available\n* Biological parameters of the past year available\n\nExclusion Criteria:\n\n* Treatment with bisphosphonate, RANKL inhibitor or SERM with bone action in the last 3 months before the transplant\n* Multiple organ transplant patients","ALL","18 Years",{"count":56,"type":57},50,"ESTIMATED","OBSERVATIONAL","The investigators project is based on:\n\n* Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA);\n* The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time;\n* Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities;\n* The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology;\n* The study of possible relationships between bone mass and muscle mass (and functioning)",[61,62],"Kidney Transplant; Complications","Bone Loss","2024-12-13",{"date":65,"type":66},"2024-12-18","ACTUAL",{"date":68,"type":66},"2020-09-01",{"date":70,"type":57},"2026-12-13",{"name":5,"class":6},1]