[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571025":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":41,"responsibleParty":57,"collaborators":24,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":24,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":24,"maxAge":24,"enrollmentInfo":67,"targetDuration":24,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":80,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"prism treatment group","ACTIVE_COMPARATOR","prism treatment",[13],"Other: prism treatment group",{"label":15,"type":16,"description":17,"interventionNames":18},"botulinum toxin group","EXPERIMENTAL","botulinum toxin injection",[19],"Procedure: botulinum toxin group",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"wearing prism glasses",[9],null,{"type":26,"name":15,"description":17,"armGroupLabels":27,"otherNames":24},"PROCEDURE",[15],[29],{"name":30,"affiliation":31,"role":32},"Wen Wen, MD, PhD","Eye & ENT Hospital of Fudan University, Shanghai, China","STUDY_CHAIR",[34,38],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","+86 (21) 3423 3133","wenweneye@126.com",{"name":39,"role":35,"phone":24,"phoneExt":24,"email":40},"Shuyang Guo, MD","m15880091363@163.com",[42],{"facility":5,"status":24,"city":43,"state":44,"zip":24,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Shanghai","China","CN",{"type":47,"coordinates":48},"Point",[49,50],121.45806,31.22222,{"lat":50,"lon":49},[53,55,56],{"name":30,"role":35,"phone":54,"phoneExt":24,"email":37},"86+(021)34233133",{"name":30,"role":35,"phone":24,"phoneExt":24,"email":24},{"name":39,"role":35,"phone":24,"phoneExt":24,"email":24},{"type":58,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100571025","botulinum-toxin-injection-versus-prism-treatment-in-small-angle-acute-acquired-concomitant-esotropia-100571025",false,"NCT06714877","Botulinum Toxin Injection Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia","A Single-center, Prospective, Randomized Controlled Trial Evaluating Type a Botulinum Toxin Injection and Prism Therapy for the Treatment of Acute Acquired Concomitant Esotropia","Inclusion Criteria:\n\n1. acute acquired concomitant esotropia diagnosis (sudden onset of esotropia or diplopia, no significant change in the degree of strabismus in each eye position, and no limitation in eye movement)\n2. strabismus angle ≤ 25PD\n3. best corrected visual acuity of both eyes ≥ 1.0\n4. intracranial disease is excluded by cranial CT or magnetic resonance imaging\n\nExclusion Criteria:\n\n1. reduction of strabismus angle by more than 10 prism diopters after refractive correction\n2. history of other ocular diseases or ocular surgeries\n3. presence of organic brain lesions or systemic diseases","ALL",{"count":68,"type":69},100,"ESTIMATED","INTERVENTIONAL",[72],"NA","This is a single-center, prospective, randomized controlled trial evaluating type A botulinum toxin injection and prism therapy for the treatment of small-angle acute acquired concomitant esotropia.\n\nSpecific Aim 1 (Primary): To compare the reduction of deviation angle and improvement of diplopia symptoms between botulinum toxin injection and prism therapy for the treatment of small-angle acute acquired concomitant esotropia.\n\nSpecific Aim 2 (Secondary): To compare the improvement of visual functions between botulinum toxin injection and prism therapy for the treatment of small-angle acute acquired concomitant esotropia.",[75],"Esotropia",[77,78,79],"Acute Acquired Concomitant Esotropia","Treatment","Botulinum Toxin Injection","NOT_YET_RECRUITING","2024-12-03",{"date":83,"type":84},"2024-12-05","ACTUAL",{"date":86,"type":69},"2024-12-10",{"date":88,"type":69},"2026-12-10",{"name":5,"class":6},1]