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This includes cone enemas, foley balloon enemas, and Transanal irrigation (e.g. Peristeen, Navina).",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":10},"An antegrade enema is a bowel management technique in which an enema is given through a surgically-created tube that enters at the start of the colon. This includes MACES, cecostomy buttons, and Chait tubes.",[15],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Josephine Hirsch","CONTACT","312-227-6076","jahirsch@luriechildrens.org",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Ilina Rosoklija","312-227-6409","irosoklija@luriechildrens.org",[38,57,68,83,98,112,127,143,158,165,180,195,210,225,240,254,268,282,296,311,326,340,355,370],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"University of Alabama at Birmingham","RECRUITING","Birmingham","Alabama","35205","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-86.80249,33.52066,{"lat":50,"lon":49},[53],{"name":54,"role":30,"phone":55,"phoneExt":10,"email":56},"Destiny Taylor","205-224-2567","destinytaylor@uabmc.edu",{"facility":58,"status":40,"city":41,"state":42,"zip":59,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"Children's of Alabama","35233",{"type":47,"coordinates":61},[49,50],{"lat":50,"lon":49},[64],{"name":65,"role":30,"phone":66,"phoneExt":10,"email":67},"Samuel Dransfield","205-641-6620","sdransfield@uabmc.edu",{"facility":69,"status":40,"city":70,"state":71,"zip":72,"country":44,"countryCode":45,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Phoenix Children's Hospital","Phoenix","Arizona","85006",{"type":47,"coordinates":74},[75,76],-112.07404,33.44838,{"lat":76,"lon":75},[79],{"name":80,"role":30,"phone":81,"phoneExt":10,"email":82},"Erica Weidler","602-933-3524","ebaimbridge@phoenixchildrens.org",{"facility":84,"status":40,"city":85,"state":86,"zip":87,"country":44,"countryCode":45,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Children's Hospital of Los Angeles","Los Angeles","California","90027",{"type":47,"coordinates":89},[90,91],-118.24368,34.05223,{"lat":91,"lon":90},[94],{"name":95,"role":30,"phone":96,"phoneExt":10,"email":97},"Kristy Azpilicueta","323-361-7079","kazpilicueta@chla.usc.edu",{"facility":99,"status":40,"city":100,"state":86,"zip":101,"country":44,"countryCode":45,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"University of California San Francisco","San Francisco","94158",{"type":47,"coordinates":103},[104,105],-122.41942,37.77493,{"lat":105,"lon":104},[108],{"name":109,"role":30,"phone":110,"phoneExt":10,"email":111},"Nicole Greco","415-347-5850","Nicole.Greco@ucsf.edu",{"facility":113,"status":40,"city":114,"state":115,"zip":116,"country":44,"countryCode":45,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"Children's Hospital of Colorado","Denver","Colorado","80218",{"type":47,"coordinates":118},[119,120],-104.9847,39.73915,{"lat":120,"lon":119},[123],{"name":124,"role":30,"phone":125,"phoneExt":10,"email":126},"Rose Prieto","720.777.2727","TeamPure@cuanschutz.edu",{"facility":128,"status":129,"city":130,"state":131,"zip":132,"country":44,"countryCode":45,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"Children's National Hospital","NOT_YET_RECRUITING","Washington D.C.","District of Columbia","20010",{"type":47,"coordinates":134},[135,136],-77.03637,38.89511,{"lat":136,"lon":135},[139],{"name":140,"role":30,"phone":141,"phoneExt":10,"email":142},"Bruce Sprague","202-476-3433","bsprague@childrensnational.org",{"facility":144,"status":40,"city":145,"state":146,"zip":147,"country":44,"countryCode":45,"cosmosGeoPoint":148,"geoPoint":152,"contacts":153},"Ann & Robert H. 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Hospital","Houston","77030",{"type":47,"coordinates":331},[332,333],-95.36327,29.76328,{"lat":333,"lon":332},[336],{"name":337,"role":30,"phone":338,"phoneExt":10,"email":339},"Jessica Kamen","832-826-2387","jessica.kamen@bcm.edu",{"facility":341,"status":129,"city":342,"state":343,"zip":344,"country":44,"countryCode":45,"cosmosGeoPoint":345,"geoPoint":349,"contacts":350},"Primary Children's Hospital","Salt Lake City","Utah","84113",{"type":47,"coordinates":346},[347,348],-111.89105,40.76078,{"lat":348,"lon":347},[351],{"name":352,"role":30,"phone":353,"phoneExt":10,"email":354},"Elizabeth Lignell","801-213-2718","Elizabeth.Lignell@hsc.utah.edu",{"facility":356,"status":40,"city":357,"state":358,"zip":359,"country":44,"countryCode":45,"cosmosGeoPoint":360,"geoPoint":364,"contacts":365},"Seattle Children's Hospital","Seattle","Washington","98105",{"type":47,"coordinates":361},[362,363],-122.33207,47.60621,{"lat":363,"lon":362},[366],{"name":367,"role":30,"phone":368,"phoneExt":10,"email":369},"Shing Varakitsomboon","206-987-0042","shing.varakitsomboon@seattlechildrens.org",{"facility":371,"status":40,"city":357,"state":358,"zip":372,"country":44,"countryCode":45,"cosmosGeoPoint":373,"geoPoint":375,"contacts":376},"University of Washington","98195",{"type":47,"coordinates":374},[362,363],{"lat":363,"lon":362},[377],{"name":378,"role":30,"phone":379,"phoneExt":10,"email":380},"Judith Hagedorn","206-744-4711","judithch@uw.edu",{"type":382,"investigatorFullName":383,"investigatorTitle":384,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","David Chu","Principal Investigator; Attending Physician, Urology; Associate Professor of Urology at Northwestern University Feinberg School of Medicine",[386],{"name":387,"class":6},"Patient-Centered Outcomes Research Institute","100622953","bowel-continence-across-the-lifespan-in-people-with-spina-bifida-100622953",false,"NCT07390318","Bowel Continence Across the Lifespan in People With Spina Bifida","Comparing Antegrade Versus Retrograde Enemas To Improve Bowel Continence Across the Lifespan in People With Spina Bifida","BCALS","Inclusion Criteria:\n\n* Minimum age 5 years old\n* Myelomeningocele diagnosis\n* Starting a retrograde or antegrade enema program (or switching from one enema program to the other)\n* English or Spanish speaking\u002Fliterate\n\nExclusion Criteria:\n\n\\- Other types of spinal dysraphism (e.g., lipomyelomeningocele, fatty filum)","ALL","5 Years",{"count":399,"type":400},943,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are:\n\n1. How well do different enema programs prevent bowel accidents?\n2. How do these enema programs affect independence, bowel symptoms, and quality of life?\n\nResearchers will compare two types of enema programs to see which works better and is easier for participants to manage.\n\nParticipants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.",[404,405,406],"Spina Bifida","Neurogenic Bowel","Bowel Incontinence",[408,409,410,411,412,413],"retrograde enema","antegrade enema","bowel management program","bowel continence program","self-management","quality of life","2026-04-17",{"date":416,"type":417},"2026-04-21","ACTUAL",{"date":419,"type":417},"2026-04-01",{"date":421,"type":400},"2030-05-01",{"name":383,"class":6},24]