[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100424326":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":45,"responsibleParty":73,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":82,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":40,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":100,"overallStatus":63,"whyStopped":40,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"3D TLSO","EXPERIMENTAL","A 3-dimensional Boston brace will be designed to the patient's individual type of scoliosis. In-brace radiographs will be performed after prescription. Reinforcement of the assigned intervention will be performed in conjunction with reassessment every 6 months. Patients are encouraged to use the brace for 20 hours per day and to also continue with physical activities for the entirety of the study. Compliance will be monitored with a heat sensor built in the brace that measures wearing time.",[13],"Device: 3D TLSO",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard TLSO","ACTIVE_COMPARATOR","A standard Boston brace will be designed to the patient's individual type of scoliosis. In brace radiographs will be performed after prescription. Reinforcement of the assigned intervention will be performed in conjunction with reassessment every 6 months. Patients are encouraged to use the brace for 20 hours per day and to also continue with physical activities for the entirety of the study. Compliance will be monitored with a heat sensor built in the brace that measures wearing time.",[19],"Device: Standard TLSO",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Brace treatment with Boston 3D 20 hours a day until skeletal maturity.",[9],[26],"Boston 3D brace",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Brace treatment with standard Boston brace 20 hours a day until skeletal maturity.",[15],[31],"Boston brace",[33],{"name":34,"affiliation":5,"role":35},"Elias Diarbakerli, PT, PhD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":34,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","+460851770000",null,"elias.diarbakerli@sll.se",{"name":43,"role":38,"phone":40,"phoneExt":40,"email":44},"Paul Gerdhem, MD, PhD","paul.gerdhem@uu.se",[46,61],{"facility":47,"status":48,"city":49,"state":40,"zip":40,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Linköping university hospital","NOT_YET_RECRUITING","Linköping","Sweden","SE",{"type":53,"coordinates":54},"Point",[55,56],15.62157,58.41086,{"lat":56,"lon":55},[59],{"name":60,"role":38,"phone":40,"phoneExt":40,"email":40},"Allan Abbott, PT, PhD",{"facility":62,"status":63,"city":64,"state":40,"zip":40,"country":50,"countryCode":51,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Karolinska university hospital","RECRUITING","Stockholm",{"type":53,"coordinates":66},[67,68],18.06871,59.32938,{"lat":68,"lon":67},[71,72],{"name":34,"role":38,"phone":40,"phoneExt":40,"email":40},{"name":43,"role":38,"phone":40,"phoneExt":40,"email":40},{"type":35,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"Paul Gerdhem","Professor",[77],{"name":78,"class":79},"Linkoeping University","OTHER_GOV","100424326","brace-treatment-for-idiopathic-scoliosis-preventing-idiopathic-scoliosis-progression-100424326",false,"NCT04805437","Brace Treatment for Idiopathic Scoliosis; PReventing Idiopathic SCOliosis PROgression","3D Designed Boston Brace Versus Standard Boston Brace in Halting Progression in Idiopathic Scoliosis: a Randomized Controlled Trial","PRISCOPRO","Inclusion Criteria:\n\n* Cobb 25-40 degrees\n* Skeletally immature, Sanders score of 6 or less and Risser 2 or less.\n* Menarche status maximum one year in females\n* Aged 9-17 years\n* No previous brace treatment or surgery for scoliosis\n* Apex of the primary curve at T7 or caudal\n\nExclusion Criteria:\n\n* Non-idiopathic scoliosis (i.e. neuromuscular, syndromic or congenital scoliosis)\n* Previous spine surgery","ALL","9 Years","17 Years",{"count":92,"type":93},170,"ESTIMATED","INTERVENTIONAL",[96],"NA","Idiopathic scoliosis is the most common spinal deformity in children and adolescents with an estimated prevalence of 3%. About one tenth of the children with scoliosis develop a deformity that requires treatment with brace or surgery with the current treatment protocol. When brace treatment for scoliosis is indicated, standard treatment consists of bracing 20 hours or more per day. Outcomes of brace treatment depend to a large extent on wearing time and since many adolescents feel uncomfortable in the brace, it is of importance to combine efficacy and comfortability of the brace.",[99],"Idiopathic Scoliosis",[101,102,103,104],"Idiopathic scoliosis","Randomized controlled trial","Brace","Orthosis","2025-02-20",{"date":107,"type":108},"2025-02-21","ACTUAL",{"date":110,"type":108},"2021-04-30",{"date":112,"type":93},"2037-04",{"name":5,"class":6},2]