[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100297567":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":47,"collaborators":51,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":10,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cerebrovascular procedure patients",null,"This is a registry. No above standard of care interventions will take place. Participants must be undergoing a clinically routine cerebrovascular procedure.",[13],"Other: Registry",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Registry","Collect standard of care clot, tissue and arterial blood during standard of care cerebrovascular procedure for lab analysis.",[9],[20],{"name":21,"affiliation":5,"role":22},"Justin F Fraser, MD","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Jennifer R Isaacs, MS, MS","CONTACT","859-323-4738","jennifer.isaacs@uky.edu",{"name":21,"role":26,"phone":30,"phoneExt":10,"email":31},"859-323-0616","jfr235@uky.edu",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":10},"University of Kentucky Deparment of Neurosurgery, UK Chandler Hospital","RECRUITING","Lexington","Kentucky","40536-0298","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-84.47772,37.98869,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Justin Fraser","Professor of Cerebrovascular, Endovascular, & Skull Base Surgery; Director, Cerebrovascular Surgery; Depts of Neurological Surgery, Neurology, Radiology, and Anatomy & Neurobiology; Center for Advanced Translational Stroke Science; Univ of KY",[52],{"name":5,"class":6},"100297567","brain-blood-and-clot-or-tissue-registry-and-collaboration-100297567",false,"NCT03153683","Brain, Blood And Clot or Tissue Registry And Collaboration","Brain, Blood And Clot or Tissue Registry And Collaboration (BACTRAC)","BACTRAC","Inclusion Criteria 1. All patients, Male or female, aged 18 years or older, undergoing cerebrovascular surgery\u002Fprocedure at the University of Kentucky.\n\nExclusion Criteria:\n\n1\\. Pregnant or breastfeeding females","ALL","18 Years",{"count":64,"type":65},1000,"ESTIMATED","OBSERVATIONAL","This is a prospective open enrollment biorepository to collect and evaluate blood and tissue collected during cerebrovascular procedures, which will then be used for the purposes of identifying biological markers, inflammatory cell infiltrates, and biological states in stroke and other cerebrovascular diseases in the human condition.\n\nThe study population will include up to 1000 subjects with cerebrovascular disease or suspected cerebrovascular disease. Male and female participants 18 years of age and older will be enrolled.\n\nThis protocol covers the procurement of biological samples from patients undergoing any cerebrovascular surgery and\u002For neurointerventional clinical procedure at University of Kentucky. Control participants will include patients undergoing non-emergent, elective diagnostic cerebral angiography as well as patients undergoing emergent angiogram cases.\n\nThis study represents the first time that tissue, clot and blood will be evaluated for the markers, proteins, and cytokines in human subjects undergoing cerebrovascular procedures.\n\nBy starting with the human condition, the investigators aim to minimize this loss in translation. Overall, this study will have a great impact on our knowledge of stroke pathology. In essence, this could fundamentally change not only how the investigators develop treatment strategies for the stroke patient population but allow us to individualize the treatment dependent on time after stroke, age, sex, and co-morbidities. Molecular techniques that are impractical when delivered systemically could be delivered locally to impede the early inflammation.\n\nThis research aims to advance understanding of cerebrovascular disease and to support the development of improved therapies.",[69,70],"Acute Ischemic Stroke","Cerebrovascular Disorders",[72,73,74,75,76,77,78,79],"Acute","Ischemic","Stroke","Biomarkers","Proteins","Inflammatory Cells","Acid\u002FBase Balance","cerebrovascular","2026-03-02",{"date":82,"type":83},"2026-03-04","ACTUAL",{"date":85,"type":83},"2017-05-11",{"date":87,"type":65},"2029-12-28",{"name":49,"class":6},1]