[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512793":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":41,"responsibleParty":76,"collaborators":78,"id":86,"slug":87,"hasResults":88,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":88,"sex":94,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":25,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":107,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"National Cancer Centre, Singapore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","The exercise intervention group will undergo an aerobic exercise and strength training programme, comprising 3 sessions per week, spanning 24 weeks (total: 3x24=72 sessions).",[13],"Behavioral: Exercise Programme",{"label":15,"type":10,"description":16,"interventionNames":17},"Control","The usual care group.",[18],"Behavioral: Control",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Exercise Programme","Aerobic exercise consists of 20-minute brisk walks or jogs (5-6 km\u002Fh) on the treadmill each session, reaching a heart rate corresponding to 50%-70% of the patient's VO2max (VO2max is determined before embarking on the exercise programme). Study participants are expected to aim for 50% VO2max at the start of the exercise programme, and gradually increasing to 70% VO2max in subsequent exercise sessions. Strength training comprises a series of circuit resistance exercises targeting the major muscle groups. Patients will perform 2-4 sets of these exercises each session, 8-10 repetitions per set. Both aerobic exercise and strength training are done in the same session. With warm-up and cool-down, each session is estimated to take up 1 hour.",[9],null,{"type":21,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Usual care group.",[15],[30],{"name":31,"affiliation":5,"role":32},"Dr Elaine LIM, MD, PhD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","+65 64368000","elaine.lim.hsuen@singhealth.com.sg",{"name":39,"role":35,"phone":25,"phoneExt":25,"email":40},"Catherine CELES","catherine.celes@nccs.com.sg",[42,59,65],{"facility":43,"status":44,"city":45,"state":25,"zip":46,"country":45,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"National University Hospital","RECRUITING","Singapore","119074","SG",{"type":49,"coordinates":50},"Point",[51,52],103.85007,1.28967,{"lat":52,"lon":51},[55],{"name":56,"role":35,"phone":57,"phoneExt":25,"email":58},"Professor Soo Chin LEE, MD","+65 67737888","ncis@nuhs.edu.sg",{"facility":60,"status":44,"city":45,"state":25,"zip":61,"country":45,"countryCode":47,"cosmosGeoPoint":62,"geoPoint":64,"contacts":25},"National Cancer Centre","168583",{"type":49,"coordinates":63},[51,52],{"lat":52,"lon":51},{"facility":66,"status":44,"city":45,"state":25,"zip":67,"country":45,"countryCode":47,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Singapore General Hospital","169608",{"type":49,"coordinates":69},[51,52],{"lat":52,"lon":51},[72],{"name":73,"role":35,"phone":74,"phoneExt":25,"email":75},"Dr Veronique TAN, MD","+65 62223322","veronique.tan.k.m@singhealth.com.sg",{"type":77,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[79,81,83,85],{"name":80,"class":6},"Singapore Cancer Society",{"name":82,"class":6},"Genome Institute of Singapore",{"name":84,"class":6},"National University of Singapore",{"name":66,"class":6},"100512793","breast-cancer-exercise-intervention-study-100512793",false,"NCT05957068","Breast Cancer Exercise Intervention Study","Breast Cancer Exercise Intervention Study (BREXINT)","BREXINT","Inclusion Criteria:\n\n* Patients with histologically or cytologically proven stage 1, 2, or 3 breast cancer\n* Patients who have undergone curative breast surgery\n* Patients who have received (neo)adjuvant chemotherapy (if given) and\u002For radiotherapy (if given)\n* Females aged 21 years and older\n* ≤ 8 weeks from breast surgery, or the last adjuvant chemotherapy or radiotherapy session, whichever is latest.\n\nExclusion Criteria:\n\n* Cardiovascular, respiratory, musculoskeletal problems that preclude moderate physical activity.\n* Major medical problems that are deemed by the investigator to be unsuitable for enrollment.","FEMALE","21 Years","99 Years",{"count":98,"type":99},2156,"ESTIMATED","INTERVENTIONAL",[102],"NA","This is a 24-week exercise programme consisting of aerobic exercise and muscle strength training, 3 sessions per week. The first 9 sessions are supervised by physiotherapists in person, followed by 63 sessions monitored remotely (video) or supervised by trainers at ActiveSG (Sport Singapore) gyms.",[105,106],"Early-stage Breast Cancer","Locally Advanced Breast Cancer",[92,108,109,110],"Muscular Strength","Cardiorespiratory Fitness","Quality of Life","2025-09-03",{"date":113,"type":114},"2025-09-05","ACTUAL",{"date":116,"type":114},"2023-07-01",{"date":118,"type":99},"2033-05-31",{"name":5,"class":6},3]