[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524931":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":23,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":23,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":23,"overallStatus":39,"whyStopped":23,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Pennington Biomedical Research Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Feeding","EXPERIMENTAL","Participants will be instructed to consume study beverages to provide \\>1.2 grams of protein per kilogram bodyweight and \\>120% of total energy needs. Energy needs will be estimated by the Mifflin-St Jeor equation multiplied by an activity factor of 1.5. Study beverages will be a mix of meal replacement shakes e.g., Ensure (Abbott Laboratories, Chicago, IL, USA) products to accommodate protein and energy needs. Study beverages will be consumed every \\~3 hours to induce a perpetually fed state. Feeding will occur during waking hours, typically between 7a-11p. Breath will be collected before, during and after the intervention.",[13],"Other: Feeding",{"label":15,"type":10,"description":16,"interventionNames":17},"Fasting","Participants will be instructed to consume only water during the duration of the Fasting Protocol. Regardless of the randomization sequence, participants will have consumed their last meal or study beverage by 11p the night prior. Breath will be collected before, during and after the intervention.",[18],"Other: Fasting",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"Nutrition beverages will be provided to meet the nutrient needs described in the Feeding Arm.",[9],null,{"type":6,"name":15,"description":25,"armGroupLabels":26,"otherNames":23},"Water will be consumed as described during the Fasting Arm.",[15],[28],{"name":29,"affiliation":5,"role":30},"Jacob Mey, PhD, RD","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":23,"email":36},"Jacob T Mey, PhD, RD","CONTACT","225-763-2644","jacob.mey@pbrc.edu",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Baton Rouge","Louisiana","70808","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-91.18747,30.44332,{"lat":49,"lon":48},[52],{"name":23,"role":34,"phone":53,"phoneExt":23,"email":54},"225-763-3000","clinicaltrials@pbrc.edu",{"type":30,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Jacob T. Mey, PhD RD","Assistant Professor - Research","100524931","breath-analysis--malnutrition-100524931",false,"NCT06115148","Breath Analysis & Malnutrition","Breath Ammonia as a Malnutrition Screening Tool","BAM-S","Inclusion Criteria:\n\n1. Age: 18-95 years\n2. Malnutrition group (Cross-sectional study only); not involved in intervention: Diagnosed with malnutrition (verified in medical history)\n\nExclusion Criteria:\n\n1. Chronic kidney, liver or pulmonary disease\n2. Anabolic steroid use other than testosterone (e.g., oxandrolone)\n3. Patients judged unsuitable for enrollment by the study medical investigator\n4. Pregnant women or women who are nursing\n5. Unable or unwilling to consume study beverages or fast for 24 hours each arm",true,"ALL","18 Years","95 Years",{"count":71,"type":72},12,"ESTIMATED","INTERVENTIONAL",[75],"NA","The purpose of this research study is to understand how breath is related to nutritional status. The procedures involved in this study include blood and breath sampling, questionnaires about health history, medications, nutritional status and diet, and a physical examination. Breath markers will be compared between individuals with and without malnutrition and be compared to indicators of malnutrition. Some individuals will undergo an interventional study involving 2 days of consuming study beverages and fasting along with providing additional breath samples to see if the breath changes in response to short-term changes in nutritional status.",[78],"Malnutrition","2026-01-16",{"date":81,"type":82},"2026-01-21","ACTUAL",{"date":84,"type":82},"2023-08-17",{"date":86,"type":72},"2026-12-30",{"name":5,"class":6},1]