[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617598":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":68,"collaborators":70,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":12,"enrollmentInfo":83,"targetDuration":12,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":95,"overallStatus":46,"whyStopped":12,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"General Practitioners Research Institute","NETWORK",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Usual care","NO_INTERVENTION","Patients are managed according to usual care for the assessment of breathlessness in general practice, without use of the Breathlessness diagnostics in a Box (BiaB) tool. Clinical assessments, diagnostic procedures, and follow-up are performed as part of routine practice. Data collected during this period are used as control data for comparison with the intervention period.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"BiaB Intervention","EXPERIMENTAL","Patients are managed using the Breathlessness diagnostics in a Box (BiaB) tool as part of routine clinical care. The BiaB intervention supports general practitioners in the diagnostic assessment of patients presenting with breathlessness. No study-mandated therapeutic interventions are applied. Outcomes during the intervention period are compared with those from the usual care period.",[18],"Diagnostic Test: Breathlessness diagnostics in a Box (BiaB)",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"DIAGNOSTIC_TEST","Breathlessness diagnostics in a Box (BiaB)","The Breathlessness diagnostics in a Box (BiaB) is a diagnostic support tool used in general practice to assist healthcare professionals in the assessment of patients presenting with breathlessness as part of routine clinical care.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Janwillem WH Kocks, Prof. Dr.","CONTACT","+31502113898","biab@gpri.nl",[32,44,58],{"facility":33,"status":34,"city":35,"state":12,"zip":12,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":12},"15 primary care sites across the Netherlands","ACTIVE_NOT_RECRUITING","Groningen","Netherlands","NL",{"type":39,"coordinates":40},"Point",[41,42],6.56667,53.21917,{"lat":42,"lon":41},{"facility":45,"status":46,"city":47,"state":12,"zip":12,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"15 primary care sites across Portugal","RECRUITING","Porto","Portugal","PT",{"type":39,"coordinates":51},[52,53],-8.61097,41.1485,{"lat":53,"lon":52},[56],{"name":57,"role":28,"phone":29,"phoneExt":12,"email":30},"GPRI",{"facility":59,"status":34,"city":60,"state":12,"zip":12,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":67,"contacts":12},"15 primary care sites across Palma De Mallorca, Madrid, Murcia","Palma de Mallorca","Spain","ES",{"type":39,"coordinates":64},[65,66],2.65024,39.56939,{"lat":66,"lon":65},{"type":69,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[71],{"name":72,"class":73},"AstraZeneca","INDUSTRY","100617598","breathlessness-diagnostics-in-a-box-biab-for-primary-care-a-multi-country-quality-improvement-project-using-a-randomized-stepped-wedge-design-100617598",false,"NCT07320703","\"Breathlessness Diagnostics in a Box\" (BiaB) for Primary Care. A Multi-country Quality Improvement Project Using a Randomized Stepped-wedge Design","BiaB","The study aims to capture the real-world heterogeneity in primary care practices and patients. Therefore, inclusion and exclusion criteria are limited.\n\nInclusion criteria\n\n* Patient must be at least 18 years old at the time of signing the informed consent.\n* Patients that present with undiagnosed dyspnea (breathlessness); or Patients who have existing diseases that could cause breathlessness, but have residual or increasing breathlessness that could be caused by other not yet detected diseases. Or HCP has doubts or requires additional tests to confirm diagnosis or to suspect new, parallel, diagnoses. For example, breathlessness in patients assessed within the framework of Cardiovascular Risk Management or for COPD monitoring\n\nExclusion criteria\n\n1. Acute worsening of previous diagnosed chronic disease where there is no suspicion of comorbidities (for example when a patient with clear COPD diagnosis has an exacerbation where typically the HCP will not perform additional tests).\n2. Inability to understand and sign the written consent form.","ALL","18 Years",{"count":84,"type":85},900,"ESTIMATED","INTERVENTIONAL",[88],"NA","This prospective stepped-wedge study evaluates whether use of the Breathlessness diagnostics in a Box (BiaB) tool shortens the time to diagnosis in patients presenting with breathlessness, compared with usual care. The study is conducted in general practice settings in the Netherlands, Spain, and Portugal. Participating sites start with a usual care period and transition sequentially to the BiaB intervention period. Data are collected during routine clinical visits, from electronic medical records, and through questionnaires completed by patients and healthcare professionals.",[91,92,93,94],"Breathlessness","Cardiovascular","Pulmonary","Mental Disease",[96,97,98,99,100,101],"breathlessness","diagnostics","cardiovascular disease","pulmonary disease","mental disease","cardiopulmonary risk","2026-01-06",{"date":104,"type":105},"2026-01-07","ACTUAL",{"date":107,"type":105},"2024-08-05",{"date":109,"type":85},"2027-04",{"name":5,"class":6},3]