[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100420252":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":42,"responsibleParty":60,"collaborators":24,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":24,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":24,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":45,"whyStopped":24,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BreEStim","EXPERIMENTAL","BreEStim is voluntary breathing controlled transcutaneous electrical nerve stimulation.",[13],"Device: BreEStim",{"label":15,"type":10,"description":16,"interventionNames":17},"EStim","EStim is transcutaneous electrical nerve stimulation.",[18],"Device: EStim",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","BreEStim will be applied for 10 to 20 minutes per session for multiple sessions",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"EStim will be applied for 10 to 20 minutes per session for multiple sessions",[15],[29],{"name":30,"affiliation":31,"role":32},"Sheng Li, MD, PhD","University of Texas","PRINCIPAL_INVESTIGATOR",[34,38],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","(713) 797-7125","sheng.li@uth.tmc.edu",{"name":39,"role":35,"phone":40,"phoneExt":24,"email":41},"Shengai Li, MS","713-797-7561","shengai.li@uth.tmc.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"The University of Texas Health Science Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-95.36327,29.76328,{"lat":55,"lon":54},[58,59],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},{"name":39,"role":35,"phone":40,"phoneExt":24,"email":41},{"type":32,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Sheng Li","Professor","100420252","breestim-for-motor-recovery-in-chronic-stroke-with-moderate-impairment-after-a-long-term-use-pilot-100420252",false,"NCT04752319","BreEStim for Motor Recovery in Chronic Stroke With Moderate Impairment After a Long-term Use (Pilot).","BreEStim for Post-Stroke Motor Recovery","Inclusion criteria:\n\n* has post stroke ≥ 6 months , medically stable;\n* Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke);\n* MAS score ≥ 1, i.e., detectable finger flexor hypertonia;\n\nExclusion criteria include:\n\n* Patients with visual deficit\u002Fneglect; hearing or cognitive impairment;\n* Patients with history of pulmonary disease (Asthma, chronic obstruction pulmonary disease, COPD);\n* Patients that are currently adjusting tone alternating medications (e.g., baclofen), or\n* Patients received botulinum toxin injection to the arm\u002Ffingers \\\u003C4 months, or phenol injections \\\u003C 2 years;\n* Patients with a pacemaker;\n* Women who are pregnant.","ALL","18 Years","75 Years",{"count":74,"type":75},4,"ESTIMATED","INTERVENTIONAL",[78],"NA","The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with moderate impairment after a long-term use.",[81],"Motor Recovery",[83,81,9],"Finger flexor spasticity","2026-06-01",{"date":86,"type":87},"2026-06-03","ACTUAL",{"date":89,"type":87},"2025-09-01",{"date":91,"type":75},"2028-03-31",{"name":5,"class":6},1]