[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618649":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":53,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Pusan National University Yangsan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Broccoli group","EXPERIMENTAL","This group takes broccoli sporout extract for 12 weeks.",[13],"Dietary Supplement: Broccoli sprout extract (BSE)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","This group takes placebo for 12 weeks.",[19],"Dietary Supplement: Placebo Control",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Broccoli sprout extract (BSE)","BSE 1,000 mg\u002Fday for 12 weeks",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo Control","Placebo (crystalline cellulosel) 1,000 mg\u002Fday for 12 weeks",[15],[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Sang Yeoup Lee, Professor, MD, PhD","CONTACT","360-2860","055","drsaylee@gmail.com",{"name":39,"role":34,"phone":35,"phoneExt":36,"email":40},"Ye Li Lee","yeri1230@gmail.com",[42],{"facility":5,"status":43,"city":44,"state":26,"zip":45,"country":46,"countryCode":26,"cosmosGeoPoint":47,"geoPoint":52,"contacts":26},"RECRUITING","Yangsan","50612","South Korea",{"type":48,"coordinates":49},"Point",[50,51],129.03358,35.34199,{"lat":51,"lon":50},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Sang Yeoup Lee","Professor","100618649","broccoli-sprout-extract-for-cognitive-function-100618649",false,"NCT07334366","Broccoli Sprout Extract for Cognitive Function","A 12-week Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Broccoli Sprout Extract on Cognitive Function Improvement in Adults With Mild Cognitive Impairment","Inclusion Criteria:\n\n* Age: Adults aged 55-85 years (inclusive), both male and female\n* Global Deterioration Scale (GDS) score of 2-3:\n\nGDS 2: Subjective memory impairment without objective evidence GDS 3: Mild objective memory impairment\n\n* Absence of dementia according to established diagnostic criteria\n* Ability to read Korean\n\nExclusion Criteria:\n\n* Severe medical conditions within the past 6 months: History of severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage), cardiac disease (angina, myocardial infarction, heart failure, arrhythmia requiring treatment), or malignancy (Note: Participants with a history of cerebrovascular or cardiac disease who are clinically stable may be included at the investigator's discretion)\n* Cognitive impairment-associated diseases: Dementia, Parkinson's disease, cerebral infarction, or other conditions associated with cognitive decline Uncontrolled hypertension: Blood pressure ≥160\u002F100 mmHg (measured after 10 minutes of rest)\n* Poor glycemic control: Fasting blood glucose ≥160 mg\u002FdL in diabetic patients\n* Uncontrolled thyroid dysfunction: Currently receiving treatment for uncontrolled hypothyroidism or hyperthyroidism\n* Renal impairment: Serum creatinine ≥2 times the upper limit of normal for the institution\n* Hepatic impairment: AST or ALT ≥2 times the upper limit of normal for the institution\n* Severe gastrointestinal symptoms: Complaints of severe heartburn, dyspepsia, or other gastrointestinal distress\n* Medications affecting cognitive function within the past month: Use of drugs (antipsychotics, anti-degenerative agents, cognitive enhancers, tricyclic antidepressants, hormone replacement therapy) or health functional foods that may influence cognitive function due to dementia or other cognitive abnormalities\n* Other clinical trial participation: Participation in other drug clinical trials within the past month or planned participation during the study period\n* Alcohol use disorder, severe\n* Food allergies: Known allergic reactions to study product components\n* Investigator discretion: Any other condition deemed inappropriate for study participation by the investigator","ALL","50 Years","85 Years",{"count":68,"type":69},100,"ESTIMATED","INTERVENTIONAL",[72],"NA","This clinical trial aims to determine whether broccoli sprout extract improves cognitive function in adults with mild cognitive impairment and to assess its safety.\n\nThe main questions are:\n\n* Does broccoli sprout extract improve cognitive function in participants?\n* What side effects occur when participants take broccoli sprout extract?",[75,76],"Cognitive Dysfunction","Cognitive Decline",[78],"cognition","2026-01-11",{"date":81,"type":82},"2026-01-13","ACTUAL",{"date":84,"type":82},"2025-04-16",{"date":86,"type":69},"2026-12-31",{"name":5,"class":6},1]