[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614860":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Sheikh Zayed Medical College","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bupivacaine + Dexmedetomidine (TAP Block)","EXPERIMENTAL","Participants in this arm will receive a combination of 20 ml of 0.25% bupivacaine and 1 mcg\u002Fkg dexmedetomidine administered via an ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management following abdominal surgery",[13],"Drug: Bupivacaine (TAP Block)",{"label":15,"type":16,"description":17,"interventionNames":18},"Bupivacaine Only (TAP Block)","ACTIVE_COMPARATOR","Participants in this arm will receive 20 ml of 0.25% bupivacaine administered via an ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management following abdominal surgery",[19],"Drug: Bupivacaine with Dexmedetomidine (TAP Block)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Bupivacaine with Dexmedetomidine (TAP Block)","A combination of 0.25% bupivacaine and 1 mcg\u002Fkg dexmedetomidine administered bilaterally via ultrasound-guided transversus abdominis plane (TAP) block to provide postoperative analgesia for abdominal surgery",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Bupivacaine (TAP Block)","10 ml of 0.25% bupivacaine administered bilaterally via ultrasound-guided transversus abdominis plane (TAP) block to provide postoperative analgesia for abdominal surgery",[9],[32],{"name":33,"affiliation":34,"role":35},"Saira Sadaf, FCPS ANESTHESIA","Shaheed Ziaur Rahman Medical College","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Rameesha Musharaf, FCPS ANESTHESIA (PGR)","CONTACT","0092-334-5038000","rameeshamusharaf96@gmail.com",[43],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Rahim Yar Khan","Punjab Province","64200","Pakistan","PK",{"type":51,"coordinates":52},"Point",[53,54],70.30345,28.41987,{"lat":54,"lon":53},[57],{"name":58,"role":39,"phone":40,"phoneExt":26,"email":41},"RAMEESHA MUSHARAF, FCPS ANESTHESIA (PGR)",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Rameesha Musharaf","POST GRADUATE RESIDENT (ANESTHESIA)","100614860","bupivacaine-with-or-without-dexmedetomidine-for-postoperative-pain-relief-in-abdominal-surgery-100614860",false,"NCT07285083","Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery","Comparison of Pain Relief by Bupivacaine With Dexmedetomidine and Bupivacaine Alone in Transversus Abdominis Plane Block for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries.","Inclusion Criteria:\n\n1. Age between 21 to 45 years.\n2. Undergoing elective abdominal surgery (exploratory laparotomy, ileostomy reversal, laparoscopic\u002Fopen cholecystectomy, mesh repair of paraumbilical hernias).\n3. The patient must be capable of providing informed consent.\n\nExclusion Criteria:\n\n1. Pregnancy.\n2. Severe allergies to local anesthetics.\n3. Pre-existing chronic pain conditions.\n4. Participation in another clinical trial within the past 30 days.","ALL","21 Years","45 Years",{"count":74,"type":75},80,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries. The research compares pain relief in two groups: one receiving a combination of bupivacaine and dexmedetomidine via a transversus abdominis plane (TAP) block, and the other receiving bupivacaine alone. The study aims to evaluate whether dexmedetomidine enhances pain relief, reduces the need for additional pain medication, and impacts sedation and side effects such as hypotension, bradycardia, and nausea. Conducted at Sheikh Zayed Medical College in Rahim Yar Khan, Pakistan, the trial will involve 80 participants and will measure pain using the Visual Analogue Scale (VAS), along with monitoring other vital parameters and complications over 12 hours post-surgery. The primary objective is to determine if the addition of dexmedetomidine provides superior pain control without significantly increasing side effects.",[81],"Pain, Postoperative",[83],"Transversus abdominis plane (TAP) block","2025-12-18",{"date":86,"type":87},"2025-12-22","ACTUAL",{"date":89,"type":87},"2024-08-01",{"date":91,"type":75},"2025-12",{"name":5,"class":6},1]