[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625169":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":21,"locations":7,"responsibleParty":31,"collaborators":33,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":7,"enrollmentInfo":69,"targetDuration":7,"studyType":72,"phases":7,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":84,"whyStopped":7,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":7},{"fullName":5,"class":6},"Leipzig Heart Science gGmbH","OTHER",null,[9,13,16,19],{"name":10,"affiliation":11,"role":12},"Holger Thiele Thiele, Prof. Dr.","University Clinic for Cardiology, Heart Center Leipzig","STUDY_DIRECTOR",{"name":14,"affiliation":11,"role":15},"Alexander Jobs Jobs, PD Dr.","STUDY_CHAIR",{"name":17,"affiliation":18,"role":15},"Raphael Twerenbold Twerenbold, Prof. Dr.","University Heart & Vascular Center Hamburg",{"name":20,"affiliation":18,"role":15},"Johannes Neumann Neumann, PD Dr.",[22,27],{"name":23,"role":24,"phone":25,"phoneExt":7,"email":26},"Holger Thiele PD Dr., Prof. Dr.","CONTACT","+49 341 865 14","Holger.Thiele@medizin.uni-leipzig.de",{"name":28,"role":24,"phone":29,"phoneExt":7,"email":30},"Alexander Jobs PD Dr., PD Dr.","+49 341 865 1428","alexander.jobs@medizin.uni-leipzig.de",{"type":32,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[34,37,39,41,43,45,47,49,51,53,55,57],{"name":35,"class":36},"Stiftung Institut für Herzinfarktforschung (evaluierendes Institut)","UNKNOWN",{"name":38,"class":36},"Herzzentrum Leipzig - Universitätsklinik für Kardiologie",{"name":40,"class":6},"Universitätsklinikum Hamburg-Eppendorf",{"name":42,"class":36},"Institut für Gesundheitsökonomie und Versorgungsforschung Medizinische Hochschule Brandenburg - Institut für Sozialmedizin und Epidemiologie",{"name":44,"class":6},"The German Heart Foundation",{"name":46,"class":36},"Bundesvereinigung der Arbeitsgemeinschaften der Notärzte Deutschlands e.V.",{"name":48,"class":36},"Wissenschaftliches Institut der AOK Bundesverband",{"name":50,"class":36},"Institute for Myocardial Infarction Research Foundation (evaluating institute)",{"name":52,"class":36},"Leipzig Heart Center - University Clinic for Cardiology",{"name":54,"class":36},"Institute for Health Economics and Health Services Research Brandenburg Medical School - Institute for Social Medicine and Epidemiology",{"name":56,"class":36},"Federal Association of Working Groups of Emergency Physicians in Germany",{"name":58,"class":36},"Scientific Institute of the AOK Federal Association","100625169","calibration-study-predict---prehospital-triage-for-suspected-acute-coronary-syndrome-without-st-segment-elevation-100625169",false,"NCT07419139","Calibration Study PREDICT - Prehospital Triage for Suspected Acute Coronary Syndrome Without ST-segment Elevation","PREDICT","Inclusion Criteria:\n\n* Suspected myocardial infarction\n* Symptom onset \\>30 minutes before arrival of emergency medical services\n* Written informed consent\n\nExclusion Criteria:\n\n* STEMI on initial ECG\n* Unstable angina, hemodynamic instability, life-threatening arrhythmias, cardiac arrest\n* Non-ischemic causes requiring hospitalization\n* Emergency physician dispatch at the request of a primary care physician\n* Age \\\u003C18 years",true,"ALL","18 Years",{"count":70,"type":71},304,"ESTIMATED","OBSERVATIONAL","The PREDICT calibration study is a prospective, non-interventional trial aiming to adapt and calibrate the ACS-Pathfinder algorithm for prehospital triage of patients with suspected non-ST-elevation acute coronary syndrome (NSTE-ACS) in Germany. Approximately 304 patients will be enrolled by six emergency medical service (EMS) stations. All patients will receive standard care and an additional point-of-care troponin test (POCT) performed in the ambulance. Clinical and biomarker data will be collected using a study app, without influencing patient management. Follow-up will be conducted up to 90 days through telephone interviews and hospital record review.\n\nThe primary objective is to determine the true prevalence of myocardial infarction and calibrate the ACS-Pathfinder algorithm accordingly. Secondary objectives include assessing feasibility, workflow, acceptance, and data processes within the EMS as preparation for a subsequent cluster-randomized main study.\n\nThe study is coordinated by Prof. Holger Thiele (Heart Center Leipzig) with co-investigators from Leipzig and Hamburg. The sponsor is Leipzig Heart Science gGmbH. Study duration is planned from January to November 2026.",[75],"Acute Coronary Syndrome Without ST Elevation on Electrocardiogram",[77,78,79,80,81,82,83],"chest pain","shortness of breath","high-sensitivity troponin","ECG changes","Myocardial infarction (MI)","Pre-hospital care","Acute coronary syndrome without ST-segment elevation","NOT_YET_RECRUITING","2026-02-10",{"date":87,"type":88},"2026-02-18","ACTUAL",{"date":90,"type":71},"2026-04",{"date":92,"type":71},"2026-11",{"name":5,"class":6}]