[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570279":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":28,"responsibleParty":59,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":86,"overallStatus":88,"whyStopped":10,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"California Institute of Technology","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Behavioral task battery",null,[12],"Behavioral: Behavioral task performance",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"BEHAVIORAL","Behavioral task performance","Measures of performance on behavioral tasks",[9],[20],{"name":21,"affiliation":5,"role":22},"John P O'Doherty, D.Phil","PRINCIPAL_INVESTIGATOR",[24],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","626-395-5981","jdoherty@hss.caltech.edu",[29,47],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"UCLA Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles","Los Angeles","California","90095","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-118.24368,34.05223,{"lat":40,"lon":39},[43],{"name":44,"role":25,"phone":45,"phoneExt":10,"email":46},"Reza Tadayon-nejad, MD PhD","310-206-6389","RTadayonNejad@mednet.ucla.edu",{"facility":48,"status":10,"city":49,"state":32,"zip":50,"country":34,"countryCode":35,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"California Insitute of Technology","Pasadena","91125",{"type":37,"coordinates":52},[53,54],-118.14452,34.14778,{"lat":54,"lon":53},[57],{"name":58,"role":25,"phone":26,"phoneExt":10,"email":27},"John O'Doherty, D Phil",{"type":22,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"John P. O'Doherty, PhD","Fletcher Jones Professor of Decision Neuroscience","100570279","can-computational-measures-of-task-performance-predict-psychiatric-symptoms-and-changes-in-symptom-severity-across-time-100570279",false,"NCT06705179","Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time","Leveraging Computationally Derived Measures of Individual Differences in Learning and Decision-making to Predict Psychiatric Diagnosis, Symptoms and Changes in Symptom Severity Across Time","CABxtime","Inclusion criteria (healthy control participants):\n\n* Age range of 18 to 65.\n* Not currently having a psychiatric diagnosis determined after psychiatric evaluation by Drs. Tadayon-Nejad and Wei (both are board certified psychiatrists).\n* Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.\n* Ability to give informed consent.\n\nExclusion criteria (healthy control participants):\n\n• Prior history and or current diagnosis of neurological disease.\n\nInclusion criteria (patients):\n\n* Age range of 18 to 65.\n* Psychiatric diagnosis of any type of depressive disorders, any type of anxiety disorders or obsessive-compulsive disorder.\n* Primary or comorbid bipolar disorders are allowed but only if not in the acute manic phase.\n* Comorbidity with autism spectrum disorder (ASD) and attention-deficit\u002Fhyperactivity disorder (ADHD) are allowed.\n* Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.\n* Ability to give informed consent.\n\nExclusion criteria (patients):\n\n* Prior history and or current diagnosis of neurological disease.\n* History or current diagnosis of psychotic disorders.\n* Currently active substance use disorder.",true,"ALL","18 Years","65 Years",{"count":75,"type":76},1100,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric symptoms and diagnoses with a longitudinal approach over a 12 month interval. Participants will be healthy participants recruited through Prolific an on-line crowdsourcing service, and psychiatric patients and healthy participants recruited via UCLA Psychiatry Clinics and UCLA's STAND Program",[82,83,84,85],"Behavior","Depressive Disorder","Anxiety Disorders","Obsessive Compulsive Disorder (OCD)",[87,9],"Computational Psychiatry","NOT_YET_RECRUITING","2024-11-21",{"date":91,"type":92},"2024-11-26","ACTUAL",{"date":94,"type":76},"2025-01-01",{"date":96,"type":76},"2029-12-31",{"name":5,"class":6},2]