[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637703":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":12,"responsibleParty":40,"collaborators":12,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":12,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":69,"whyStopped":12,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":12},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Micro-Incision Cataract Surgery (MICS) with standardized surgical incisions","NO_INTERVENTION","Main incision (1.8mm wide) is placed at the edge of the cornea, in an angle of 170 degrees (90 degrees is at 12 o´clock position, upwards). A minimal sideport is created at the edge of the cornea, approximately 90 degrees from the main incision.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"MICS with surgical incisions tailored according to corneal astigmatismus","EXPERIMENTAL","For corneal astigmatismus with steep meridian axis in the interval 61-119 degrees, main incision (1.8mm wide) is placed in the steep axis. For astigmatismus larger than 1.5 dioptres, the main incision is enlarged to 2.75mm before placement of intra-ocular lens.\n\nFor corneal astigmatismus with steep meridian axis in the intervals 0-60 degrees and 120-179 degrees, main incision (1.8mm wide) is placed in the steep axis. Before placement of intra-ocular lens, a corresponding incision is made at the edge of the cornea opposite to (180 degrees from) the primary main incision. For astigmatismus larger than 1.5 dioptres, the main incision is enlarged to 2.75mm before placement of intra-ocular lens, and the opposite incision is made to measure 2.75mm.",[18],"Procedure: Adapted clear corneal incisions",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","Adapted clear corneal incisions","For corneal astigmatismus with steep meridian axis in the interval 61-119 degrees, main incision (1.8mm wide) is placed in the steep axis. For astigmatismus larger than 1.5 dioptres, the main incision is enlarged to 2.75mm before placement of intra-ocular lens. For corneal astigmatismus with steep meridian axis in the intervals 0-60 degrees and 120-179 degrees, main incision (1.8mm wide) is placed in the steep axis. Before placement of intra-ocular lens, a corresponding incision is made at the edge of the cornea opposite to (180 degrees from) the primary main incision. For astigmatismus larger than 1.5 dioptres, the main incision is enlarged to 2.75mm before placement of intra-ocular lens, and the opposite incision is made to measure 2.75mm.",[14],[26],{"name":27,"affiliation":28,"role":29},"Björn Johansson, MD PhD FEBO","Department of Biomedical and Clinical Sciences, Division of Sensory Organs and Communication, Medical Faculty of Linköping University, Sweden","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":12,"email":35},"Björn Johansson, MD PhD Phebo","CONTACT","+46 10 1031254","bjorn.johansson@regionostergotland.se",{"name":37,"role":33,"phone":38,"phoneExt":12,"email":39},"Helen Setterud, PhD, Assistant professor","+46 10 1038682","helen.setterud@regionostergotland.se",{"type":29,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Björn Johansson","Associate professor, Senior consultant","100637703","can-tailored-surgical-incisions-reduce-refractive-error-and-dependence-on-glasses-after-cataract-surgery-100637703",false,"NCT07623317","Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?","A Prospective Randomized Controlled Study of How Construction and Placement of Surgical Corneal Incisions May Influence Refractive Errors and Spectacle Dependence After Cataract Surgery","AST-2","Inclusion Criteria:\n\n* Visually disturbing cataract\n* Corneal and refractive astigmatismus more than 1 dioptre\n* Able and willing to undergo study procedures and measurements 3 weeks and 12 weeks after cataract surgery.\n\nExclusion Criteria:\n\n* Declining to participate\n* concomitant disease that prevents detailed objective and subjective investigations (e.g. dementia, serious ocular comorbidity limiting expected postoperative visual acuity to below 20\u002F40)\n* condition damaging structural integrity of cornea (surgical complications, infection, trauma, previous corneal disease)","ALL","40 Years","90 Years",{"count":55,"type":56},100,"ESTIMATED","INTERVENTIONAL",[59],"NA","Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes. As the corneal curvature is the main source for astigmatism after cataract surgery, our aim is to investigate whether postoperative astigmatism can be reduced by tailoring the location of surgical incisions according to the curvature of the cornea. We also wish to investigate whether this in turn reduces the need for glasses following cataract surgery.\n\nIn the planned study, one group of patients with cataracts and concurrent corneal astigmatism will undergo surgery using customized incision placement, while a control group will be operated on using standard incision placement without consideration of corneal astigmatism. Astigmatism will be measured before surgery and again at 3 and 12 weeks postoperatively. We will also assess how tailored incisions affect corneal biomechanics and shape, as well as measure visual quality and the need for glasses during daily activities before and after surgery.\n\nApproximately 160,000 cataract procedures are performed annually in Sweden. Around 40% of these patients (64,000 individuals) have astigmatism greater than 1 diopter and could potentially achieve improved surgical outcomes based on the results of this study. The method is cost-effective and associated with a low risk of complications compared to other approaches for reducing astigmatism.",[62,63],"Cataract (Post-operative Cataract Surgery Follow-up)","Refraction Error",[65,66,67,68],"Cataract","Micro-Incision Cataract Surgery","Astigmatismus","Spectacle dependence","NOT_YET_RECRUITING","2026-05-28",{"date":72,"type":73},"2026-06-03","ACTUAL",{"date":75,"type":56},"2026-09-15",{"date":77,"type":56},"2027-09-30",{"name":5,"class":6}]