[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100482292":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":23,"responsibleParty":40,"collaborators":7,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":7,"enrollmentInfo":53,"targetDuration":7,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":65,"whyStopped":7,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Ottawa Hospital Research Institute","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Venkatesh Thiruganasambandamoorthy, CCFP-EM, MSc","PRINCIPAL_INVESTIGATOR",[13,19],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},"Iris Nguyen, BSc","CONTACT","613-798-5555","17766","pnguyen@ohri.ca",{"name":20,"role":15,"phone":16,"phoneExt":21,"email":22},"Jane Park, BHSc","19347","junpark@ohri.ca",[24],{"facility":5,"status":7,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Ottawa","Ontario","K1Y 4E9","Canada","CA",{"type":31,"coordinates":32},"Point",[33,34],-75.69812,45.41117,{"lat":34,"lon":33},[37,38,39],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},{"name":20,"role":15,"phone":16,"phoneExt":21,"email":22},{"name":10,"role":11,"phone":7,"phoneExt":7,"email":7},{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"SPONSOR_INVESTIGATOR","Venkatesh Thiruganasambandamoorthy","Principal Investigator","100482292","canadian-prehospital-syncope-risk-score-prehospital-csrs-100482292",false,"NCT05560126","Canadian Prehospital Syncope Risk Score (Prehospital CSRS)","Validation of the Canadian Prehospital Syncope Risk Score","Inclusion Criteria:\n\n* Patients who access paramedic services through the 911 system will be included if they have suffered syncope, defined as a sudden transient loss of consciousness followed by spontaneous complete recovery.\n\nExclusion Criteria:\n\n* Pediatric patients (\\\u003C18 years old),\n* Patients who have a prolonged period of unconsciousness (\\>5 minutes),\n* Change in mental status from baseline, witnessed seizure,\n* Loss of consciousness due to head trauma (i.e., trauma was the initial event),\n* or if unable to provide accurate details due to language barrier, cognitive impairment, alcohol, or drug intoxication.","ALL","18 Years",{"count":54,"type":55},4875,"ESTIMATED","OBSERVATIONAL","Background: Syncope is defined as a sudden, brief loss of consciousness (LOC) followed by a rapid complete recovery. It accounts for 160,000 emergency department (ED) visits each year in Canada. Despite this, few people are hospitalized (\\~15%) and even fewer will die (\\~1%). Two-thirds of patients with syncope arrive at the ED by calling 911. There are many causes of syncope. Identifying patients at low risk for bad outcomes would allow paramedics to safely determine which patients need care in the ED from those who can remain home. The research team recently developed the Canadian Prehospital Syncope Risk Score (CPSRS) which accurately identified patients at low risk for 30-day serious outcomes.\n\nObjective: The goal of this study is to validate the accuracy of the CPSRS in the prehospital setting or refine if needed to predict the risk of 30-day serious outcomes for patients with syncope.\n\nMethods: The research team will enroll patients with syncope from five paramedic services across Canada (British Columbia - Vancouver and Kelowna areas only, London-Middlesex, York Region, Frontenac, and Ottawa). The research team will exclude patients \\\u003C18 years old, LOC \\>5 minutes, changes in mental status from baseline, alcohol or drug intoxication, or language barrier. Paramedics will fill out a study data collection form with the CPSRS items and additional data should the tool need refinement. The data will be entered into a secure database and will assess patient outcomes (death and potentially life-threatening medical conditions) at 30 days. The research team will examine model accuracy using standard prediction measures and look to improve model accuracy if needed. The research team expects to enroll 4875 patients over a 1-year recruitment period based on annual call volumes.\n\nExpected Outcomes: Once validated, the tool could reduce the number of patients transported to the hospital by identifying those at low risk. This would improve patient-oriented care, while at the same time saving valuable paramedic and ED resources.",[59],"Syncope",[59,61,62,63,64],"Emergency Medicine Services","Prehospital","Risk-stratification","Emergency Department","NOT_YET_RECRUITING","2025-07-29",{"date":68,"type":69},"2025-07-31","ACTUAL",{"date":71,"type":55},"2025-09-01",{"date":73,"type":55},"2027-09-30",{"name":42,"class":6},1]