[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554606":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":33,"responsibleParty":50,"collaborators":20,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":20,"enrollmentInfo":62,"targetDuration":20,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":35,"whyStopped":20,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"East and North Hertfordshire NHS Trust","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"all eligible patients with non stenotic eosinophilic oesophagitis","OTHER","single arm observational study",[13],"Device: capsule sponge",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","capsule sponge","capsule sponge sampling device of the oesophagus",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Danielle Morris, MD FRCP","East and North Herts NHS Trust","PRINCIPAL_INVESTIGATOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Toral Odedra","CONTACT","01438 314333","toral.odedra@nhs.net",{"name":28,"role":29,"phone":20,"phoneExt":20,"email":31},[34],{"facility":24,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Stevenage","Hertfordshire","SG1 4AB","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-0.20256,51.90224,{"lat":45,"lon":44},[48],{"name":23,"role":29,"phone":20,"phoneExt":20,"email":49},"danielle.morris@nhs.net",{"type":51,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100554606","capsule-sponge-study-in-eosinophilic-oesophagitis-100554606",false,"NCT06501274","Capsule Sponge Study in Eosinophilic Oesophagitis","A Pragmatic Interventional Study to Assess the Clinical Value of Capsule Sponge in the Assessment of Response to Treatment of Non-stenotic Eosinophilic Oesophagitis in a Single District General Hospital","Cosie","Inclusion Criteria:\n\n• patients diagnosed with non -stenotic eosinophilic oesophagitis who have a change in treatment\n\nExclusion Criteria:\n\n* Strictures or rings at most recent endoscopy that prevent passage of adult gastroscope\n* Previous oesophageal dilatation\n* Previous oesophageal perforation or surgical resection\n* Oesophago-gastric malignancy\n* Oesophageal varices\n* Bolus obstruction since last endoscopy requiring hospital visit\n* Previous fundoplication or complicated hiatus hernia\n* Patient on Warfarin with INR\\>=3\n* Suspected new diagnosis of EOE without prior endoscopic confirmation","ALL","18 Years",{"count":63,"type":64},140,"ESTIMATED","INTERVENTIONAL",[67],"NA","Open pragmatic, descriptive single site study in adult patients with non-stenotic eosinophilic oesophagitis.\n\nTo assess the clinical value of Capsule sponge in the assessment of treatment response in patients with known non-stenosing eosinophilic oesophagitis, as an alternative to gastroscopy in a real world setting.\n\nTo assess patient preference for Capsule sponge or gastroscopy. All patients with non-stenosing eosinophilic oesophagitis who are reviewed in clinic that have not had reassessment of their oesophagus post treatment initiation or change in treatment will be offered Capsule sponge as an alternative to gastroscopy.\n\nA standardised clinical symptom questionnaire will be self-administered for 2w prior to clinic visits and Capsule sponge.\n\nTelephone triage for safety check and exclusion criteria by Capsule sponge nurse.\n\nA patient symptom questionnaire at the time of procedure by research nurse. A patient satisfaction survey will be delivered after the Capsule sponge procedure by Capsule sponge nurse.\n\nCytological assessment of the Capsule sponge and eosinophil count and other markers of inflammation will be reported by Cyted.\n\nClinic follow up will occur at approximately 6-8 weeks post Capsule sponge. Descriptive Changes in management as a result of the Capsule sponge findings and \u002For symptoms will be recorded by clinician.",[70],"Eosinophilic Esophagitis",[17],"2024-07-08",{"date":74,"type":75},"2024-07-15","ACTUAL",{"date":77,"type":75},"2023-07-31",{"date":79,"type":64},"2025-07-31",{"name":5,"class":6},1]