[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630893":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":7,"locations":17,"responsibleParty":33,"collaborators":36,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":72,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Herlev and Gentofte Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"HFpEF Observational Measurements","Observational measurements including collection of blood for biomarker and genetic analyses, echocardiography, ECG, and extraction of clinical data from electronic health records (comorbidities, medications, and prior hospitalizations). No treatment or procedure is assigned; all data reflect routine care and participant characteristics.",[13],{"name":14,"affiliation":15,"role":16},"Emil Wolsk, MD, PhD","Department of Cardiology, Herlev and Gentofte Hospital, Copenhagen, Denmark","PRINCIPAL_INVESTIGATOR",[18],{"facility":5,"status":7,"city":19,"state":7,"zip":7,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"Copenhagen","Denmark","DK",{"type":23,"coordinates":24},"Point",[25,26],12.56553,55.67594,{"lat":26,"lon":25},[29],{"name":14,"role":30,"phone":31,"phoneExt":7,"email":32},"CONTACT","38683868","emil.wolsk@regionh.dk",{"type":16,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Emil Wolsk","Specialist Cardiologist",[37,39,41,43,45],{"name":38,"class":6},"Aalborg University Hospital",{"name":40,"class":6},"Aarhus University Hospital",{"name":42,"class":6},"Odense University Hospital",{"name":44,"class":6},"Rigshospitalet, Denmark",{"name":46,"class":6},"Zealand University Hospital","100630893","capture-hfpef-national-study-of-identification-and-phenotyping-of-heart-failure-with-preserved-ejection-fraction-100630893",false,"NCT07493590","CAPTURE-HFpEF: National Study of Identification and Phenotyping of Heart Failure With Preserved Ejection Fraction","CAPTURE-HFpEF (Cardiovascular Assessment and Phenotyping for Timely Understanding and Recognition of Evolving Heart Failure With Preserved Ejection Fraction)","CAPTURE-HFpEF","Inclusion Criteria:\n\n* Patients \\>60 years with ≥1 risk factor, OR\n* Patients \\>50 years with ≥2 risk factors\n* Hypertension\n* Type 1 or 2 diabetes\n* Chronic kidney disease (eGFR \\\u003C60 mL\u002Fmin\u002F1.73 m²)\n* Previous cardiotoxic drug exposure\n* atrial fibrillation\n* Ischemic heart disease\n* Previous heart valve surgery\u002Fintervention\n* Body mass index \\>30 kg\u002Fm² (self-reported)\n* Use of ≥40 mg furosemide\n* Obstructive sleep apnea\n* Non-alcoholic fatty liver disease\n\nExclusion Criteria:\n\n* Cancer \\\u003C1 year\n* Dialysis\n* COPD and O2\n* Nursing home\n* Age \\>90 years\n* Dementia\n* Known dilated cardiomyopathy\n* Prior organ-transplantation\n* Amyloidosis","ALL","18 Years","90 Years",{"count":59,"type":60},30000,"ESTIMATED","10 Years","OBSERVATIONAL","The goal of this observational study is to improve early detection, characterization, and understanding of heart failure with preserved ejection fraction (HFpEF) in adults at risk of or diagnosed with HFpEF, including men and women across Danish regions.\n\nThe main questions to answer are:\n\nCan systematic cardiovascular screening and deep phenotyping improve early identification and classification of HFpEF?\n\nWhich clinical, imaging, biomarker, and metabolic characteristics define subtypes (phenotypes) of HFpEF and predict disease progression and outcomes?\n\nResearchers will compare participants with HFpEF, participants at risk of HFpEF, and relevant control groups to see if differences in biomarkers, imaging findings, and clinical characteristics can identify early disease stages and distinct HFpEF phenotypes.\n\nParticipants identified with HFpEF will:\n\n* Undergo detailed cardiovascular examinations (e.g., echocardiography, CT and other imaging examinations, RHC, CPET)\n* Provide blood and tissue samples for biomarker and metabolic analyses\n* Complete clinical assessments and questionnaires\n* Have relevant health data collected from national health registries\n* Attend follow-up assessments to monitor disease progression",[65],"Heart Failure With Preserved Ejection Fraction (HFPEF)",[67,68,69,70,71],"Heart failure","Heart Failure with Preserved Ejection Fraction (HFpEF)","Cardiovascular Mortality","Cardiovascular Disease","Chronic Heart Failure","NOT_YET_RECRUITING","2026-03-23",{"date":75,"type":76},"2026-03-25","ACTUAL",{"date":78,"type":60},"2026-04-01",{"date":80,"type":60},"2035-04-01",{"name":5,"class":6},1]