[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584026":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":51,"collaborators":55,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":12,"enrollmentInfo":76,"targetDuration":12,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":34,"whyStopped":12,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Utah","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Neuroethical Assessment Group","NO_INTERVENTION","Patients with epilepsy who have Neuropace RNS implants who will be surveyed about the neuroethics of real-world multi-modal recordings to assess their attitude toward research data sharing and confidentiality.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Multi-Modal Recording System Assessment Group","EXPERIMENTAL","Patients with epilepsy who have Neuropace RNS implants, and patients without epilepsy\u002FRNS implants, who will participate in real-world navigation and autobiographical memory tasks in order to evaluate the reliability and signal quality of the multi-modal recording system.",[18],"Behavioral: Free and Cued Recall Memory. Temporal Sequence and Spatial Memory",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","Free and Cued Recall Memory. Temporal Sequence and Spatial Memory","Memory for real-world episodic experiences will be tested in the laboratory first with free recall (spoken narration of their recollections from each environment) and then with cued recall, in which participants will be cued with an event image from the CAPTURE app, a map location, or a relative time and asked to recall the other two non-cued pieces of episodic information (event, place, or time). Because we will know the 'ground truth', the cued recall test will allow us to measure how accurately the participant is able to remember key details of each episode. We will also assess temporal order memory by asking participants to arrange 1st person images in the order in which they occurred, and we will assess spatial memory by asking them to place each image on a schematic map of the venue.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Alireza Kazemi, PhD","CONTACT","5303040970","alireza.kazemi@utah.edu",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Clinical Neurosciences Center, University of Utah","RECRUITING","Salt Lake City","Utah","84132","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-111.89105,40.76078,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":12,"email":50},"Cory S Inman, PhD","801-581-8939","inmanneurolab@gmail.com",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Cory Inman","Assistant Professor",[56,59,61,63],{"name":57,"class":58},"National Institutes of Health (NIH)","NIH",{"name":60,"class":58},"National Institute of Mental Health (NIMH)",{"name":62,"class":6},"University of California, San Diego",{"name":64,"class":6},"University of California, Los Angeles","100584026","capturing-autobiographical-memory-formation-in-real-world-spaces-using-multimodal-recordings-100584026",false,"NCT06883981","Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings","Capturing Autobiographical Memory Formation in People Moving Through Real-World Spaces Using Synchronized Wearables and Intracranial Recordings of EEG","CAPTURE","Inclusion Criteria:\n\n* 18 years of age or older\n* healthy to minor cognitive impairment\n\nExclusion Criteria:\n\n* younger than 18 years of age\n* more than minor cognitive impairment",true,"ALL","18 Years",{"count":77,"type":78},50,"ESTIMATED","INTERVENTIONAL",[81],"NA","The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted neurostimulation devices (e.g., NeuroPace RNS) for epilepsy treatment. The main questions it aims to answer are:\n\nHow does the brain encode and retrieve real-world autobiographical memories? Can multimodal data integration enhance our understanding of memory-related cognitive and neural mechanisms?\n\nParticipants will:\n\n* Use a smartphone-based recording application (CAPTURE app) to collect real-world data.\n* Have their wearable sensor data (e.g., audio-visual, accelerometry, GPS, autonomic physiology, eye tracking) synchronized with invasive neural recordings.\n\nResearchers will analyze these multimodal data streams to develop new analytic approaches for studying memory formation in naturalistic settings, with the long-term goal of informing neuromodulation-based memory enhancement treatments for individuals with memory disorders.",[84,85],"Epilepsy","Autobiographical Memory",[87,88,89,84,90,91,92,93,94],"Autobiographical memory","Memory","IEEG","Real-World Navigation","Spatial Memory","Hippocampus","Medial Temporal Cortex","Multi-Modal Recording","2025-04-03",{"date":97,"type":98},"2025-04-08","ACTUAL",{"date":100,"type":98},"2025-01-30",{"date":102,"type":78},"2028-03",{"name":5,"class":6},1]