[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559630":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":61,"collaborators":10,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":10,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational cohort",null,"Inclusion criteria:\n\n≥18 years of age Suspected NSTEMI (signs and symptoms suggest of ACS with initial ECG showing no ST-elevation) Planned ICA where CMR can be performed without delaying ICA Able to provide written informed consent\n\nExclusion criteria:\n\nContraindications for CMR examination with gadolinium contrast (claustrophobia, eGFR \\\u003C30ml\u002Fmin\u002F1.73m2, contrast allergy, and non-MRI compatible implants) Arrythmias which hinder CMR examination Previous CABG Hemodynamic instability Myocardial infarction \\\u003C6 months prior to inclusion",[13],"Diagnostic Test: Cardiac MRI (CMR) examination",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Cardiac MRI (CMR) examination","An MRI examination of the heart (CMR) is presently performed as a follow-up examination in patients where an invasive coronary angiography (ICA) shows no obstructive findings. The intervention in this study is characterized by having the CMR performed before, rather than after, the ICA.\n\nIn addition, this study will implement some novel CMR sequences which have not been previously tested in this patient cohort:\n\n* CMR Angiography (imaging the coronary arteries using MRI)\n* CMR Fingerprinting (sequences which perform T1 and T2 mapping simultaneously)",[9],[21,22,23,24,25,26,27],"cmr","cardiac mri","cmr angiography","cmr fingerprinting","fingerprinting","t1 mapping","t2 mapping",[29],{"name":30,"affiliation":31,"role":32},"Marcus E Carlsson, Professor","Karolinska Insitutet and Karolinska University Hospital","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Daniel F Andersson, M.D.","CONTACT","+46 735958647","daniel.f.andersson@ki.se",[40],{"facility":41,"status":42,"city":43,"state":10,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Karolinska University Hospital","RECRUITING","Stockholm","171 64","Sweden","SE",{"type":48,"coordinates":49},"Point",[50,51],18.06871,59.32938,{"lat":51,"lon":50},[54,56,58,59],{"name":35,"role":36,"phone":55,"phoneExt":10,"email":38},"46+735958647",{"name":30,"role":36,"phone":10,"phoneExt":10,"email":57},"marcus.carlsson@ki.se",{"name":30,"role":32,"phone":10,"phoneExt":10,"email":10},{"name":35,"role":60,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":62,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100559630","cardiac-mri-prior-to-invasive-coronary-angiography-in-patients-with-suspected-non-st-elevation-myocardial-infarction-100559630",false,"NCT06566625","Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction","The Karolinska Pilot Study for Cardiac Magnetic Resonance Imaging Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction","KaPSICA-CMR","Inclusion Criteria:\n\n* ≥18 years of age Suspected NSTEMI (signs and symptoms suggest of ACS with initial ECG showing no ST-elevation)\n* Planned ICA where CMR can be performed without delaying ICA\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Contraindications for CMR examination with gadolinium contrast (claustrophobia, eGFR \\\u003C30ml\u002Fmin\u002F1.73m2, contrast allergy, and non-MRI compatible implants)\n* Arrythmias which hinder CMR examination\n* Previous CABG\n* Hemodynamic instability\n* Myocardial infarction \\\u003C6 months prior to inclusion","ALL","18 Years",{"count":74,"type":75},150,"ESTIMATED","OBSERVATIONAL","Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions (STEMI and NSTEMI, respectively) using an ECG. While patients with STEMI are urgently referred to a cath lab, patients with NSTEMI usually undergo a planned invasive coronary angiography (ICA) anywhere from 24-72 hours after arriving to the hospital. When an invasive coronary angiography can not explain the cause of a myocardial infarction, an MRI of the heart (a CMR) is often done as a follow-up investigation.\n\nA growing body of evidence suggests that performing a CMR before the planned ICA can provide an accurate diagnosis and defer the need for an ICA in many of these patients with NSTEMI.",[79,80],"Non-ST Elevation Myocardial Infarction","Acute Coronary Syndrome",[82,83,84,85,86,87,88,80,89,90,91,92,93,94,95,96,97,98,99],"CMR","MRI","Cardiac MRI","Cardiac Magnetic Resonance","Cardiac Magnetic Resonance imaging","AMI","ACS","NSTEMI","Non-STEMI","ICA","Invasive Coronary Angiography","Coronary Angiography","T1","T2","Magnetic Resonance Fingerprinting","Native T1","Native T2","Magnetic Resonance Angiography","2024-08-21",{"date":102,"type":103},"2024-08-22","ACTUAL",{"date":105,"type":103},"2024-07-17",{"date":107,"type":75},"2025-12",{"name":5,"class":6},1]