[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541967":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":10,"centralContacts":29,"locations":38,"responsibleParty":56,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Karlstad Central Hospital","OTHER",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Preoperative EF: 50% or higher",null,"Patients included will be examined with Transthoracic Echocardiography preoperatively and Ejection Fraction (EF) measured.",[13],"Device: Esophageal Doppler",{"label":15,"type":10,"description":11,"interventionNames":16},"Patients with Preoperative EF: 45% or lower",[13],{"label":18,"type":10,"description":19,"interventionNames":20},"Patients without intrathecal bupivacain and morphine.","The routine is that all patient receive an intrathecal injection of morphine and bupivacain before start of anesthesia. Patients who have contraindications for spinal anesthesia will be collected in this group.",[13],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","Esophageal Doppler","Esophageal Doppler: measuring cardiac performance. INVOS: measuring regional saturation of the brain.",[15,9,18],[28],"InVivo Optical Spectroscopy INVOS",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Ragnar N Henningsson, Associate Professor","CONTACT","+46108317434","ragnar.henningsson@regionvarmland.se",{"name":36,"role":32,"phone":10,"phoneExt":10,"email":37},"Ann-Sofie Lorentzon, ND","Ann-Sofie.Lorentzon@regionvarmland.se",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Dpt of Anesthesiology&Intensive Care; Central Hospital of Karlstad","RECRUITING","Karlstad","Värmland County","65230","Sweden","SE",{"type":48,"coordinates":49},"Point",[50,51],13.50357,59.3793,{"lat":51,"lon":50},[54],{"name":31,"role":32,"phone":55,"phoneExt":10,"email":34},"+461083317434",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ragnar Henningsson","Associate Professor","100541967","cardiac-performance-during-steep-trendelenburg-position-in-patients-undergoing-robotic-surgery-surgery-100541967",false,"NCT06336746","Cardiac Performance During Steep Trendelenburg Position in Patients Undergoing Robotic Surgery Surgery.","Effects of Steep Trendelenburg and Pneumoperitoneum on Cardiac Performance During Robotic-assisted Surgery in Patients With Normal and Low Ejection Fraction.","Inclusion Criteria:\n\n1\\. Consecutive Patients Scheduled for Robotic Surgery with Trendelenburg positioning.\n\n\\-\n\nExclusion Criteria:\n\n1. Age \\\u003C18;\n2. Dementia,\n3. Not able to give written consent -",true,"ALL","18 Years",{"count":71,"type":72},80,"ESTIMATED","OBSERVATIONAL","The field of robotic-assisted laparoscopic surgery increases all the time. Older and more fragile patients which are not suitable for major open surgery could be scheduled for robotic- assisted surgery. The peroperative anesthesiological challenges and stresses during this type of surgery could anyway be even more prominent.\n\nThe extreme positioning of patients during robotic surgery in the pelvis, often 30 degrees head down tilting (Trendelenburg positioning), should increase the work load of the heart significantly. There are no studies concerning fragile patients with heart failure during these conditions.\n\nIn this study the circulatory effects in patients with normal heart function and preexisting heart failure will be studied during robotic surgery in extreme Trendelenburg positioning\n\nDuring surgery the work load and performance of the heart will be monitored using an esophageal doppler and optical spectrophotometry measuring regional saturation of the brain. This study can identify patients at risk of developing critical circulatory failure during this type of surgery.",[76,77],"Heart Failure, Systolic","Robotic Surgery","2026-02-10",{"date":80,"type":81},"2026-02-12","ACTUAL",{"date":83,"type":81},"2024-11-21",{"date":85,"type":72},"2026-12-31",{"name":5,"class":6},1]