[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561688":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":60,"collaborators":28,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":28,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":28,"enrollmentInfo":71,"targetDuration":28,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":28,"overallStatus":81,"whyStopped":28,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Corewell Health East","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Radiation Therapy at 15 Gy for Ventricular Tachycardia","EXPERIMENTAL","Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 15 Gy",[13],"Radiation: Stereotactic Body Radiation Therapy (SBRT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Radiation Therapy at 20 Gy for Ventricular Tachycardia","Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 20 Gy",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Radiation Therapy at 25 Gy for Ventricular Tachycardia","Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 25 Gy",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"RADIATION","Stereotactic Body Radiation Therapy (SBRT)","Stereotactic body radiation therapy, which delivers precise, high-dose radiation non-invasively to generate thermal scarring to myocardial targets causing VT",[9,15,19],null,[30],{"name":31,"affiliation":32,"role":33},"John Robertson, MD","Corewell Health William Beaumont University Hospital","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":28,"email":39},"John Roberston, MD","CONTACT","248-551-7038","john.robertson@corewellhealth.org",{"name":41,"role":37,"phone":42,"phoneExt":28,"email":43},"Kristen Grant, RN","248-551-0439","kristen.grant@corewellhealth.org",[45],{"facility":32,"status":28,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Royal Oak","Michigan","48073","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-83.14465,42.48948,{"lat":55,"lon":54},[58],{"name":31,"role":37,"phone":59,"phoneExt":28,"email":39},"(248) 551-7038",{"type":33,"investigatorFullName":31,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Clinical Director, Radiation Oncology","100561688","cardiac-radioablation-for-vt-100561688",false,"NCT06593418","Cardiac Radioablation for VT","A Phase I\u002FII Study of Cardiac Radioablation for Refractory Ventricular Tachycardia","Inclusion Criteria:\n\n* Participants must be 18 years or older.\n* Automatic implanted cardiac defibrillator present.\n* VT is monomorphic with at least two episodes of VT within an eight week (56 day) period as recorded by an AICD or heart failure related to VT or VT storm.\n* Ejection fraction ≥20%.\n* At least one previous cardiac ablation for VT.\n* VT refractory despite antiarrhythmic medications.\n* Likely to live for 12 months in the absence of VT.\n* AICD in a position in the chest RT to be given without direct radiation.\n* Woman of reproductive age must ensure that she won't become pregnant or breastfeed at the time of RT.\n* The participant has no contraindications to a Cardiac MRI as per routine Cardiology practice.\n\nExclusion Criteria:\n\n* Class IV heart failure\n* Abandoned leads.\n* Prior radiation therapy to the chest or upper abdomen.\n* Interstitial lung disease.","ALL","18 Years",{"count":72,"type":73},24,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this interventional study is to determine the minimum dose necessary for successful cardiac radioablation of refractory ventricular tachycardia (VT) and to study the utility of target volume definition using Delayed Enhancement Cardiac MRI (DE-CMR) .",[79,80],"Ventricular Tachycardia","Myocardial Infarction","NOT_YET_RECRUITING","2026-04-15",{"date":84,"type":85},"2026-04-20","ACTUAL",{"date":87,"type":73},"2026-07",{"date":89,"type":73},"2028-01",{"name":5,"class":6},1]