[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556185":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":10,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Queen Mary University of London","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Renal Disease or Cardiology Disease",null,"This study aims to assess, in a real-world setting, the safety, efficacy and feasibility of further investigations in patients with renal disease and cardiac disease.",[13],"Other: Observation",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"Observation",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Krishnaraj Rathod, MBBS, PhD","CONTACT","02073777000","k.s.rathod@qmul.ac.uk",[25],{"facility":26,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Barts Health NHS Trust","RECRUITING","London","EC1A 7BE","United Kingdom","UK",{"type":33,"coordinates":34},"Point",[35,36],-0.12574,51.50853,{"lat":36,"lon":35},[39],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":40},"k.s.rathod@qmil.ac.uk",{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100556185","cardio-renal-registry-100556185",false,"NCT06521801","Cardio-Renal Registry","Barts Health Cardio-Renal Registry","BHCRR","Informed consent will not be sought for, as patients are automatically included onto a database that we will use for research purposes. No children will be included in this study. Vulnerable adults or those unable to give consent will be included in the study as well if they are referred to the Nephrology team.\n\nInclusion Criteria:\n\n1. Both male and female patients ≥16 years of age will be included\n2. All patients will be reviewed by the Nephrology team a the RLH with renal disease.\n\nExclusion Criteria:\n\n1\\. Patients \\\u003C16 years will not be included in this study.","ALL","16 Years",{"count":54,"type":55},60000,"ESTIMATED","12 Weeks","OBSERVATIONAL","Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality risk progressively increases with worsening CKD. As glomerular filtration rate (GFR) declines the probability of developing coronary artery disease (CAD) increases linearly, and patients with GFR \\\u003C60 mL\u002Fmin\u002F1.73 m2 have 2-3-fold increased CV mortality risk, relative to patients without CKD. Management of CAD is complicated in CKD patients due to the likelihood of comorbid conditions and potential for side effects. Despite their high cardiovascular risk, ACS patients with renal dysfunction are less commonly treated with guideline-based medical therapy and are less frequently referred for coronary revascularisation. This observation, referred to as the \"treatment risk paradox,\" has been well described and may be explained by physicians' concerns regarding possible nonrenal side effects as well as renal toxicities. Furthermore, patients with severe CKD have traditionally been under-represented in most large cardiovascular clinical trials. Therefore, recommendations for both medical and revascularisation of CAD have relied heavily on extrapolation of results from the non-CKD population.\n\nThis data will add to that literature by assessing the characteristics and outcomes of patients with CAD and CKD. It will also identify and characterise predictors of outcomes, improve risk stratification and diagnostic evaluation.",[60,61,62,63,64,65],"End Stage Renal Disease","Cardio-Renal Syndrome","Myocardial Infarction","Cerebrovascular Accident","Percutaneous Coronary Intervention","Dialysis","2026-01-05",{"date":68,"type":69},"2026-01-07","ACTUAL",{"date":71,"type":69},"2024-08-01",{"date":73,"type":55},"2030-06-01",{"name":5,"class":6},1]