[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100414889":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":31,"centralContacts":45,"locations":51,"responsibleParty":267,"collaborators":269,"id":279,"slug":280,"hasResults":281,"nctId":282,"briefTitle":283,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":281,"sex":286,"minAge":287,"maxAge":10,"enrollmentInfo":288,"targetDuration":291,"studyType":292,"phases":10,"briefSummary":293,"conditions":294,"keywords":296,"overallStatus":54,"whyStopped":10,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":313},{"fullName":5,"class":6},"Tufts Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiogenic Shock Patients",null,"Cardiogenic Shock patients eligible for this study are defined by at least one of the two categories below.\n\n1. Patients have at least 2 of the following concurrently at any point during the index hospitalization: MAP \\\u003C 60mmHg or a \\>30mmHg drop in MAP from baseline, SBP \\\u003C 90mmHg or a \\>30mmHg drop in SBP from baseline, Pulse \\> 100, Cardiac Index \\\u003C 2.2, Cardiac Power Output ≤ 0.6 or PAPI \\\u003C 1.0.\n2. Patients require the use of at least 1 vasopressor, inotrope or acute mechanical circulatory support device to maintain values above the above targets.",[13,14,15],"Drug: Vasopressor","Drug: Inotrope","Device: Acute Mechanical Circulatory Support Devices",[17,22,26],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DRUG","Vasopressor","The vasopressors include phenylephrine, norepinephrine, epinephrine, dopamine and vasopressin.",[9],{"type":18,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Inotrope","Inotropes include dobutamine and milrinone.",[9],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"DEVICE","Acute Mechanical Circulatory Support Devices","Acute Mechanical Circulatory Support devices include ECMO (VV), ECMO (VA), Impella CP, Impella 2.5, Impella 5.0, Impella 5.5, Impella RP, IABP, Centrimag, Tandem Heart and ProTek Duo.",[9],[32,36,39,42],{"name":33,"affiliation":34,"role":35},"Reshad Garan, MD","Beth Israel Deaconess Medical Center","STUDY_DIRECTOR",{"name":37,"affiliation":38,"role":35},"Claudius Mahr, DO","University of Washington",{"name":40,"affiliation":41,"role":35},"Jaime Hernandez-Montfort, MD","Cleveland Clinic Foundation-Florida",{"name":43,"affiliation":44,"role":35},"Daniel Burkhoff, MD PhD","CardioVascular Research Foundation",[46],{"name":47,"role":48,"phone":49,"phoneExt":10,"email":50},"Navin K Kapur, MD","CONTACT","6176368252","nkapur@tuftsmedicalcenter.org",[52,71,86,96,110,124,134,148,161,174,188,198,212,226,240,254],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Cleveland Clinic Florida","RECRUITING","Weston","Florida","33331","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-80.39977,26.10037,{"lat":64,"lon":63},[67,69],{"name":68,"role":48,"phone":10,"phoneExt":10,"email":10},"Jaime Hernandez-Montfort, MD MPH",{"name":68,"role":70,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":72,"status":54,"city":73,"state":74,"zip":75,"country":58,"countryCode":59,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Northwestern Medicine","Chicago","Illinois","60611",{"type":61,"coordinates":77},[78,79],-87.65005,41.85003,{"lat":79,"lon":78},[82,84],{"name":83,"role":48,"phone":10,"phoneExt":10,"email":10},"Esther Vorovich, MD",{"name":85,"role":70,"phone":10,"phoneExt":10,"email":10},"Esther Vorovich",{"facility":87,"status":54,"city":73,"state":74,"zip":88,"country":58,"countryCode":59,"cosmosGeoPoint":89,"geoPoint":91,"contacts":92},"University of Chicago","60612",{"type":61,"coordinates":90},[78,79],{"lat":79,"lon":78},[93,95],{"name":94,"role":48,"phone":10,"phoneExt":10,"email":10},"Sandeep Nathan, MD",{"name":94,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":97,"status":54,"city":98,"state":99,"zip":100,"country":58,"countryCode":59,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Maine Medical Center","Portland","Maine","04102",{"type":61,"coordinates":102},[103,104],-70.2589,43.65737,{"lat":104,"lon":103},[107,109],{"name":108,"role":48,"phone":10,"phoneExt":10,"email":10},"Andrew Schwartzman, MD",{"name":108,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":54,"city":111,"state":112,"zip":113,"country":58,"countryCode":59,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Boston","Massachusetts","02111",{"type":61,"coordinates":115},[116,117],-71.05977,42.35843,{"lat":117,"lon":116},[120,122],{"name":47,"role":48,"phone":121,"phoneExt":10,"email":50},"6176366140",{"name":123,"role":70,"phone":10,"phoneExt":10,"email":10},"Navin Kapur, MD",{"facility":34,"status":54,"city":111,"state":112,"zip":125,"country":58,"countryCode":59,"cosmosGeoPoint":126,"geoPoint":128,"contacts":129},"02215",{"type":61,"coordinates":127},[116,117],{"lat":117,"lon":116},[130,132],{"name":131,"role":48,"phone":10,"phoneExt":10,"email":10},"Arthur R Garan",{"name":133,"role":70,"phone":10,"phoneExt":10,"email":10},"Arthur R Garan, MD",{"facility":135,"status":54,"city":136,"state":137,"zip":138,"country":58,"countryCode":59,"cosmosGeoPoint":139,"geoPoint":143,"contacts":144},"Hackensack Meridian Health","Hackensack","New Jersey","07601",{"type":61,"coordinates":140},[141,142],-74.04347,40.88593,{"lat":142,"lon":141},[145,147],{"name":146,"role":48,"phone":10,"phoneExt":10,"email":10},"Haroon Faraz, MD",{"name":146,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":149,"status":54,"city":150,"state":150,"zip":151,"country":58,"countryCode":59,"cosmosGeoPoint":152,"geoPoint":156,"contacts":157},"Columbia University Irving Medical Center","New York","10032",{"type":61,"coordinates":153},[154,155],-74.00597,40.71427,{"lat":155,"lon":154},[158,160],{"name":159,"role":48,"phone":10,"phoneExt":10,"email":10},"Justin Fried, MD",{"name":159,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":162,"status":54,"city":98,"state":163,"zip":164,"country":58,"countryCode":59,"cosmosGeoPoint":165,"geoPoint":169,"contacts":170},"Providence St. Vincent Heart Clinic","Oregon","97225",{"type":61,"coordinates":166},[167,168],-122.67621,45.52345,{"lat":168,"lon":167},[171,173],{"name":172,"role":48,"phone":10,"phoneExt":10,"email":10},"Jacob Abraham, MD",{"name":172,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":175,"status":54,"city":176,"state":177,"zip":178,"country":58,"countryCode":59,"cosmosGeoPoint":179,"geoPoint":183,"contacts":184},"Allegheny General Hospital","Pittsburgh","Pennsylvania","15212",{"type":61,"coordinates":180},[181,182],-79.99589,40.44062,{"lat":182,"lon":181},[185,187],{"name":186,"role":48,"phone":10,"phoneExt":10,"email":10},"Manreet Kanwar, MD",{"name":186,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":189,"status":54,"city":176,"state":177,"zip":190,"country":58,"countryCode":59,"cosmosGeoPoint":191,"geoPoint":193,"contacts":194},"University Of Pittsburgh Medical Center","15261",{"type":61,"coordinates":192},[181,182],{"lat":182,"lon":181},[195,197],{"name":196,"role":48,"phone":10,"phoneExt":10,"email":10},"Gavin Hickey, MD",{"name":196,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":199,"status":54,"city":200,"state":201,"zip":202,"country":58,"countryCode":59,"cosmosGeoPoint":203,"geoPoint":207,"contacts":208},"Baylor Scott & White Advanced Heart Failure Clinic","Dallas","Texas","75201",{"type":61,"coordinates":204},[205,206],-96.80667,32.78306,{"lat":206,"lon":205},[209,211],{"name":210,"role":48,"phone":10,"phoneExt":10,"email":10},"Detlef Wencker, MD",{"name":210,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":213,"status":54,"city":214,"state":201,"zip":215,"country":58,"countryCode":59,"cosmosGeoPoint":216,"geoPoint":220,"contacts":221},"University of Texas Medical Branch","Galveston","77555",{"type":61,"coordinates":217},[218,219],-94.7977,29.30135,{"lat":219,"lon":218},[222,224],{"name":223,"role":48,"phone":10,"phoneExt":10,"email":10},"Wissam Khalife, MD",{"name":225,"role":48,"phone":10,"phoneExt":10,"email":10},"Wissam Khalife",{"facility":227,"status":54,"city":228,"state":201,"zip":229,"country":58,"countryCode":59,"cosmosGeoPoint":230,"geoPoint":234,"contacts":235},"Houston Methodist Hospital","Houston","77030",{"type":61,"coordinates":231},[232,233],-95.36327,29.76328,{"lat":233,"lon":232},[236,238],{"name":237,"role":48,"phone":10,"phoneExt":10,"email":10},": Ju H Kim, MD",{"name":239,"role":70,"phone":10,"phoneExt":10,"email":10},"Ju H Kim, MD",{"facility":241,"status":54,"city":242,"state":243,"zip":244,"country":58,"countryCode":59,"cosmosGeoPoint":245,"geoPoint":249,"contacts":250},"Inova Health System","Falls Church","Virginia","22042",{"type":61,"coordinates":246},[247,248],-77.17109,38.88233,{"lat":248,"lon":247},[251,253],{"name":252,"role":48,"phone":10,"phoneExt":10,"email":10},"Shashank Sinha, MD, MSc",{"name":252,"role":70,"phone":10,"phoneExt":10,"email":10},{"facility":255,"status":54,"city":256,"state":257,"zip":258,"country":58,"countryCode":59,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"University of Washington Medical Center","Seattle","Washington","98195-9472",{"type":61,"coordinates":260},[261,262],-122.33207,47.60621,{"lat":262,"lon":261},[265,266],{"name":37,"role":48,"phone":10,"phoneExt":10,"email":10},{"name":37,"role":70,"phone":10,"phoneExt":10,"email":10},{"type":268,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[270,273,275,277],{"name":271,"class":272},"Abbott","INDUSTRY",{"name":274,"class":272},"Boston Scientific Corporation",{"name":276,"class":272},"Abiomed Inc.",{"name":278,"class":6},"Getinge Group","100414889","cardiogenic-shock-working-group-registry-100414889",false,"NCT04682483","Cardiogenic Shock Working Group Registry","CSWG","Inclusion Criteria:\n\n* Patients must have cardiogenic shock.\n\nCardiogenic shock is defined by at least one of the two categories below:\n\n1. At least 2 of the following concurrently at any point during the index hospitalization:\n\n   * Cardiac Index \\\u003C 2.2\n   * PAPI \\\u003C 1.0\n   * Cardiac Power Output ≤ 0.6\n   * MAP \\\u003C 60mmHg or a \\>30mmHg drop in MAP from baseline\n   * SBP \\\u003C 90mmHg or a \\>30mmHg drop in SBP from baseline\n   * Pulse \\> 100\n2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.\n\nPost-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.","ALL","18 Years",{"count":289,"type":290},5000,"ESTIMATED","1 Year","OBSERVATIONAL","The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.",[295],"Cardiogenic Shock",[295,297,298,299,300,301,302,303],"mechanical circulatory support","hemodynamics","heart failure","acute myocardial infarction","registry","critical care","clinical outcomes research","2025-06-03",{"date":306,"type":307},"2025-06-06","ACTUAL",{"date":309,"type":307},"2017-12-04",{"date":311,"type":290},"2026-06-01",{"name":5,"class":6},16]