[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617119":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":50,"collaborators":53,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":69,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":82,"overallStatus":86,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of L'Aquila","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with ischemic stroke occuring within 28 days after cardiological interventional procedures",null,"Cardiological interventions includes: Percutaneuous Coronary Intervention - PCI, Transcatheter Aortic Valve Replacement - TAVR, Baloon Aortic Valvuloplasy - BAV, Percutaneous Mitral Valve Repair or Replacement, Patent Formaen Ovale - PFO - or Atrial Septal Defects - ASD - Closure, Left Atrial Appendage Closure, Transcatheter Pulmonary Valve Replacement, Percutaneous Closure of Paravalvular Leaks",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Matteo Foschi, MD","CONTACT","+390863499322","matteo.foschi@graduate.univaq.it",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Department of Biotechnological and Applied Clinical Sciences","L’Aquila","L'Aquila","67100","Italy","IT",{"type":27,"coordinates":28},"Point",[29,30],13.39954,42.35055,{"lat":30,"lon":29},[33,36,40,43,46,48],{"name":34,"role":15,"phone":16,"phoneExt":10,"email":35},"Simona Sacco, MD","simona.sacco@univaq.it",{"name":37,"role":15,"phone":38,"phoneExt":10,"email":39},"Raffaele Ornello, MD, PhD","+390683499322","raffaele.ornello@univaq.it",{"name":41,"role":42,"phone":10,"phoneExt":10,"email":10},"Lucio D'Anna, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":44,"role":45,"phone":10,"phoneExt":10,"email":10},"Federico De Santis, MD","SUB_INVESTIGATOR",{"name":47,"role":45,"phone":10,"phoneExt":10,"email":10},"Francesca Gabriele, MD",{"name":49,"role":45,"phone":10,"phoneExt":10,"email":10},"Paola Colantuono, MD",{"type":42,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Simona Sacco","Full Professor of Neurology",[54],{"name":55,"class":56},"Rete delle NeuroCardiologie","UNKNOWN","100617119","cardiological-interventions-and-acute-stroke-treatment-study-100617119",false,"NCT07314476","CardioLogical Interventions and Acute strOke Treatment sTudy","CLOT","Inclusion Criteria:\n\n* acute ischemic stroke in adult patient (18 years of age or older) as diagnosed according to the World Health Organization (WHO) criteria;\n* stroke with evidence of CT\u002FMRI DWI\u002FFLAIR acute lesion in the first neuroimaging or in the follow-up at 24-48 h;\n* interventional cardiological procedures performed within 28 days since the stroke onset (Percutaneuous Coronary Intervention - PCI, Transcatheter Aortic Valve Replacement - TAVR, Baloon Aortic Valvuloplasy - BAV, Percutaneous Mitral Valve Repair or Replacement, Patent Formaen Ovale - PFO - or Atrial Septal Defects - ASD - Closure, Left Atrial Appendage Closure, Transcatheter Pulmonary Valve Replacement, Percutaneous Closure of Paravalvular Leaks);\n* written informed consent provided by the patient himself or by proxy (for unconscious patients, cognitively impaired, or aphasic).\n\nExclusion Criteria:\n\n* Stroke-like symptoms due primarily to another non-ischemic\u002Fhemorrhagic acute neurological condition or stroke mimics (e.g. severe hypo- or hyperglycemia, migraine with aura, functional disorders, etc);\n* Spontaneous and post traumatic hemorrhagic stroke or spontaneous\u002Fpost-traumatic subarachnoid hemorrhage or subdural hematoma;\n* AciuImpossibility to achieve written informed consent","ALL","18 Years",{"count":67,"type":68},400,"ESTIMATED","180 Days","OBSERVATIONAL","The study aims to investigate characteristics and prognosis of ischemic stroke cases following cardiological interventions, focusing on the effectiveness and safety of acute ischemic stroke treatments.",[73,74,75,76,77,78,79,80,81],"Acute Ischemic Stroke AIS","Stroke Treatment","PCI Patients","Aortic Valve Replacement","Transcatheter Aortic Valve Replacement (TAVR)","Mitral Valve Repair","Mitral Valve Replacement","Left Atrial Appendage Closure","Transcatheter Pulmonary Valve Replacement (TPVR)",[83,84,85],"acute ischemic stroke","acute ischemic stroke treatments","cardiological intervention","NOT_YET_RECRUITING","2026-01-04",{"date":89,"type":90},"2026-01-07","ACTUAL",{"date":92,"type":68},"2026-01",{"date":94,"type":68},"2028-12",{"name":5,"class":6},1]