[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570039":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":64,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":10,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":10,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"St. Anne's University Hospital Brno, Czech Republic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"coronary artery bypass graft candidates",null,"patients scheduled for CABG surgery will undergo pre-operative cardiopulmonary exercise testing and post-operative complications monitoring",[13],"Diagnostic Test: Cardiopulmonary exercise testing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Cardiopulmonary exercise testing","Subjects will undergo pre-operative cardiopulmonary exercise testing.",[9],[21],{"name":22,"affiliation":23,"role":24},"Ivan Cundrle, prof., M.D.","St. Anne's University Hospital","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","00420 543182553","Ivan.Cundrle@fnusa.cz",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Marek Lukes, M.D.","00 420 543 182 484","marek.lukes@cktch.cz",[35,57],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":10,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Centre of Cardiovascular and Transplantation Surgery","RECRUITING","Brno","Czech Republic","60200","Czechia",{"type":43,"coordinates":44},"Point",[45,46],16.60796,49.19522,{"lat":46,"lon":45},[49,51,54,56],{"name":31,"role":27,"phone":32,"phoneExt":10,"email":50},"mare.lukes@fnusa.cz",{"name":52,"role":53,"phone":10,"phoneExt":10,"email":10},"Petr Fila, M.D., Ph.D.","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":10,"phoneExt":10,"email":10},"Marek Sebo, M.D.",{"name":31,"role":24,"phone":10,"phoneExt":10,"email":10},{"facility":58,"status":59,"city":38,"state":39,"zip":60,"country":41,"countryCode":10,"cosmosGeoPoint":61,"geoPoint":63,"contacts":10},"St. Anne's University Hospital in Brno","ACTIVE_NOT_RECRUITING","61200",{"type":43,"coordinates":62},[45,46],{"lat":46,"lon":45},{"type":24,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ivan Cundrle","Principal Investigator",[68],{"name":69,"class":6},"Centre of Cardiovascular and Transplantation Surgery, Czech Republic","100570039","cardiopulmonary-exercise-testing-in-cardiosurgery-patients-100570039",false,"NCT06702059","Cardiopulmonary Exercise Testing in Cardiosurgery Patients","Cardiopulmonary Exercise Testing in the Prediction of Post-operative Complications in Patients Undergoing Coronary Artery Bypass Graft Surgery","Inclusion Criteria:\n\n* patients scheduled for coronary artery bypass graft surgery\n\nExclusion Criteria:\n\n* not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery","ALL","18 Years",{"count":80,"type":81},130,"ESTIMATED","OBSERVATIONAL","Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE\u002FVCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications.\n\nWhether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.",[85],"Postoperative Complications",[87,88,89],"cardiovascular surgery","cardiopulmonary exercise testing","post-operative complications","2025-05-12",{"date":92,"type":93},"2025-05-15","ACTUAL",{"date":95,"type":93},"2024-12-01",{"date":97,"type":81},"2028-04-01",{"name":5,"class":6},2]