[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558323":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":31,"collaborators":7,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":38,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":7,"studyType":46,"phases":7,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"University Hospital, Brest","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"anne Henckes","CONTACT","02 98 34 70 98","anne.henckes@chu-brest.fr",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"CHRU de Brest","RECRUITING","Brest","29909","France","FR",{"type":23,"coordinates":24},"Point",[25,26],-4.48628,48.39029,{"lat":26,"lon":25},[29],{"name":30,"role":11,"phone":7,"phoneExt":7,"email":7},"Anne Henckes",{"type":32,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100558323","cardiotoxicity-of-carbon-monoxide-in-patients-treated-with-hyperbaric-oxygen-therapy-100558323",false,"NCT06549621","Cardiotoxicity of Carbon Monoxide in Patients Treated With Hyperbaric Oxygen Therapy","COCARDIOTOX","Inclusion Criteria:\n\nPatients treated for CO poisoning with HBOT in the hyperbaric and underwater medicine department of the Brest University hospital from 2015\u002F01\u002F01 to 2021\u002F12\u002F31\n\nExclusion Criteria:\n\n* refusal","ALL","18 Years","100 Years",{"count":44,"type":45},66,"ESTIMATED","OBSERVATIONAL","Carbon monoxide poisoning is a frequent domestic accident and the leading cause of death from unintentionnal poisoning. Its toxicity is based on the CO binding to hemoglobin and myoglobin, inhibition of mitochondrial cytochrome oxidase, resulting in tissue hypoxia and reduced adenosine triphosphate synthesis and ischemia-reperfusion injury.\n\nThis study aims to investigate the early and late cardiologic effects of CO in patients treated with hyperbaric oxygen (HBOT) for CO poisoning",[49],"Carbon Monoxide Poisoning",[51,52],"cardiac injury","cardiac toxicity","2024-08-08",{"date":55,"type":56},"2024-08-12","ACTUAL",{"date":58,"type":56},"2022-07-25",{"date":60,"type":45},"2024-10-25",{"name":5,"class":6},1]