[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493544":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"IRCCS Policlinico S. Donato","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy",null,"60 healthy subjects; age \\>18; sinus rhythm; absence of autonomic diseases or dysfunctions.",[13],"Diagnostic Test: active standing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","active standing","Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Vlasta Bari, PhD","CONTACT","+390252774381","vlasta.bari@grupposandonato.it",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"IRCCS Policlinico San Donato","RECRUITING","San Donato Milanese","Milan","20097","Italy","IT",{"type":36,"coordinates":37},"Point",[38,39],9.26838,45.41047,{"lat":39,"lon":38},[42,43,46],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"name":44,"role":45,"phone":10,"phoneExt":10,"email":10},"Marco Ranucci, MD","SUB_INVESTIGATOR",{"name":22,"role":47,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":47,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Vlasta Bari","Assistant Professor, PhD","100493544","cardiovascular-and-cerebrovascular-control-in-healthy-subjects-100493544",false,"NCT05706532","Cardiovascular and Cerebrovascular Control in Healthy Subjects","Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects","CardioSan","Inclusion Criteria:\n\n* age \\>18\n* sinus rhythm\n* informed consent signed\n\nExclusion Criteria:\n\n* age \\\u003C18\n* presence of autonomic nervous system diseases or dysfunctions",true,"ALL","18 Years",{"count":63,"type":64},60,"ESTIMATED","OBSERVATIONAL","The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability.\n\nTo this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge.\n\nThe interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.",[9,68,69],"Autonomic Nervous System","Cerebral Autoregulation",[71,72,73,74],"autonomic nervous system","heart rate variability","cerebral autoregulation","peripheral resistances","2025-03-25",{"date":77,"type":78},"2025-03-28","ACTUAL",{"date":80,"type":78},"2023-05-29",{"date":82,"type":64},"2027-10",{"name":5,"class":6},1]