[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618348":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":10,"centralContacts":21,"locations":27,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":59,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients who did not develop acute kidney injury(AKI) after cardiovascular surgery",null,[12],"Other: Observation",{"label":14,"type":10,"description":10,"interventionNames":15},"Patients who developed AKI after cardiovascular surgery",[12],[17],{"type":6,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"Observation","As an observational study, patients' therapeutic approach will not be modified during the course of this research.",[14,9],[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Sheng Liu","CONTACT","8613501331366","liusheng@fuwai.com",[28],{"facility":29,"status":10,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Fuwai Hospital, Chinese Academy of Medical Science","Beijing","Beijing Municipality","100444","China","CN",{"type":36,"coordinates":37},"Point",[38,39],116.39723,39.9075,{"lat":39,"lon":38},[42],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},{"type":44,"investigatorFullName":23,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100618348","cardiovascular-surgery-early-prediction-system-for-aki-cards-aki-registry-100618348",false,"NCT07330453","Cardiovascular Surgery Early Prediction System for AKI :CARDS-AKI Registry","Early Prediction and Clinical Outcomes of Cardiovascular Surgery-Associated Acute Kidney Injury: A Prospective Multicenter Cohort Study","Inclusion Criteria:\n\n* Age ≥ 18 years；\n* Scheduled to undergo elective cardiac surgery；\n* Able to complete baseline data collection and provide written informed consent.\n\nExclusion Criteria:\n\n* Preoperative serum creatinine \\> 353 μmol\u002FL, history of or currently receiving dialysis therapy.\n* History of kidney transplantation.\n* Presence of malignant tumors.",true,"ALL","18 Years",{"count":57,"type":58},5000,"ESTIMATED","2 Years","OBSERVATIONAL","This multicenter, prospective study prospectively enrolled patients undergoing cardiovascular surgery. Detailed perioperative clinical data and biospecimens were collected at multiple time points. The primary aim is to develop an early warning model for postoperative acute kidney injury (AKI) by integrating clinical data and biomarkers. Additionally, through long-term follow-up, the study seeks to characterize outcome trajectories and establish a prognostic model for AKI patients.\n\nThis study addresses four key questions: 1) Integration of clinical information and biomarkers to develop an early predictive model for cardiac surgery-associated acute kidney injury (CSA-AKI); 2) Identification of risk factors for CSA-AKI occurrence; 3) Determinants of prognosis in patients with CSA-AKI; and 4) Enhanced prediction of near- and long-term clinical event risks in this patient population.\n\nParticipants will receive standard perioperative management. The study protocol includes the following procedures:(1) Clinical Data Collection: Comprehensive perioperative clinical data will be systematically recorded. (2) Biospecimen Sampling: Serial blood and urine samples will be obtained at predefined time points throughout the perioperative period. (3) In-Hospital Monitoring: Clinical outcomes will be continuously monitored during the hospital stay. (3) Post-discharge Follow-up: Participants will be assessed at regular intervals after discharge to track the occurrence of major adverse events.\n\nThese findings provide a foundational basis for the development of a data-driven early-warning system. Such a system is designed to facilitate the prompt identification of high-risk patients and enable the initiation of personalized treatment strategies, thereby potentially improving clinical outcomes and optimizing resource allocation",[63],"Cardiovascular Surgery","NOT_YET_RECRUITING","2026-01-04",{"date":67,"type":68},"2026-01-09","ACTUAL",{"date":70,"type":58},"2025-12-25",{"date":72,"type":58},"2029-07-31",{"name":5,"class":6},1]