[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563738":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":14,"collaborators":17,"id":24,"slug":25,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":30,"eligibilityCriteria":31,"healthyVolunteers":26,"sex":32,"minAge":7,"maxAge":7,"enrollmentInfo":33,"targetDuration":7,"studyType":36,"phases":7,"briefSummary":37,"conditions":38,"keywords":40,"overallStatus":46,"whyStopped":7,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":7},{"fullName":5,"class":6},"Guangzhou Institute of Respiratory Disease","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Zhibin Xu","CONTACT","+8615816832640","unignorable_xuzhibin@outlook.com",{"type":15,"investigatorFullName":10,"investigatorTitle":16,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Professor",[18,20,22],{"name":19,"class":6},"The Second People's Hospital of Foshan",{"name":21,"class":6},"First People's Hospital of Foshan",{"name":23,"class":6},"Maternal and Child Health Hospital of Foshan","100563738","causal-relationship-between-plasma-vegf-family-proteins-and-placenta-previa-a-two-sample-mendelian-randomization-study-100563738",false,"NCT06620068","Causal Relationship Between Plasma VEGF Family Proteins and Placenta Previa: A Two-Sample Mendelian Randomization Study","Causal Association Between Plasma Vascular Endothelial Growth Factor Family Proteins and Placenta Previa: A Two-Sample Mendelian Randomization Study","VEGF PP","Inclusion Criteria:\n\n* Participants included in genome-wide association studies (GWAS) with available data on plasma VEGF family proteins and placenta previa.\n\nExclusion Criteria:\n\n* Participants with incomplete or missing data on plasma VEGF levels or placenta previa.","ALL",{"count":34,"type":35},207473,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the causal relationship between plasma vascular endothelial growth factor (VEGF) family proteins and placenta previa using a two-sample Mendelian randomization (MR) approach. Genome-wide association study (GWAS) data will be analyzed to assess the correlation and potential causality between VEGF protein levels and the occurrence of placenta previa.",[39],"Placenta Previa",[41,42,43,44,45],"Vascular Endothelial Growth Factor (VEGF)","Mendelian Randomization","Angiogenesis","Pregnancy Complications","Placental Development","NOT_YET_RECRUITING","2024-09-26",{"date":49,"type":50},"2024-10-01","ACTUAL",{"date":52,"type":35},"2024-09-25",{"date":54,"type":35},"2024-12-01",{"name":5,"class":6}]