[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536811":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":12,"locations":24,"responsibleParty":163,"collaborators":12,"id":165,"slug":166,"hasResults":167,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":167,"sex":173,"minAge":174,"maxAge":175,"enrollmentInfo":176,"targetDuration":12,"studyType":179,"phases":180,"briefSummary":182,"conditions":183,"keywords":12,"overallStatus":27,"whyStopped":12,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":194},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"OPT","NO_INTERVENTION","Orthopantomogram = current recommended clinical examination approach (comparator procedure)",null,{"label":14,"type":15,"description":16,"interventionNames":17},"CBCT","EXPERIMENTAL","Cone Beam Computed Tomography = experimental clinical examination approach (procedure under evaluation)",[18],"Diagnostic Test: CBCT",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"DIAGNOSTIC_TEST","Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF.",[14],[25,43,56,69,82,95,108,124,137,150],{"facility":26,"status":27,"city":28,"state":12,"zip":12,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"CHU Bordeaux - 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Patients hospitalized or recently hospitalized for definite IE according to the 2015 ESC classification, naive patients for dental examination and imaging, whatever the IE responsible microorganism;\n2. Patients with a stable clinical state, meaning stabilized IE patients out of the critical phase, compatible with the performance of an OPT and a CBCT;\n3. Patients whose life expectancy is expected to be longer than 6 months;\n4. Patients who agree to visit the dental department of the hospital to carry out OIF eradication or at his\u002Fher personal dentist;\n5. Patients over 18 years old;\n6. Patients affiliated to a Social Security or a health insurance scheme;\n7. Patients who have given informed consent to participate to the study.\n\nExclusion Criteria:\n\n1. OPT or CBCT already performed before the inclusion of the patients in the study and available for the investigator during the patient's hospitalization.\n2. Medical contraindications to perform OPT or CBCT imaging;\n3. Absence of microbiologic identification of the IE responsible microorganism;\n4. Pregnant or breastfeeding women;\n5. Patients unable to give informed consent to participate to the study (under trusteeship, guardianship and legal protection).","ALL","18 Years","100 Years",{"count":177,"type":178},170,"ESTIMATED","INTERVENTIONAL",[181],"NA","1\\. Infective Endocarditis (IE) is a rare and serious disease with high morbidity and mortality; 2. Streptoccoci of oral origin are the second more frequent microorganisms responsible for IE; 3. Oral Infectious Foci (OIF) are underdetected using the current recommended clinical examination\u002FOrthopantomogram (OPT) approach; 4. Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF than OPT; 5. To date, no study has been performed to assess the potential benefit of a clinical examination\u002FCBCT approach on the oral health status in IE patients.\n\nThus, conducting a randomized controlled trial is highly desirable to assess the potential impact of a clinical examination\u002FCBCT approach on the oral health status of patients hospitalized for IE and potentially to reduce IE new episodes.",[184],"Infective Endocarditis","2026-03-31",{"date":187,"type":188},"2026-04-06","ACTUAL",{"date":190,"type":188},"2024-12-18",{"date":192,"type":178},"2028-07-18",{"name":5,"class":6},10]