[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100474294":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":36,"responsibleParty":60,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":25,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Vanderbilt University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cognitive behavioral therapy plus social cognitive training (CBTSCT)","EXPERIMENTAL","The cognitive behavioral therapy is based on Beck's cognitive therapy model for the treatment of depression. We will conduct individual therapy with depressed adolescents using modules from the Coping with Stress manual used in other depression treatment studies with adolescents. In addition, therapists will teach teens explicitly about theory of mind and social perspective taking during each session and will use examples from the teen's own life to help them learn the skills.",[13],"Behavioral: Cognitive behavioral therapy plus social cognitive training (CBTSCT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Cognitive behavioral therapy (CBT)","ACTIVE_COMPARATOR","The cognitive behavioral therapy is based on Beck's cognitive therapy model for the treatment of depression. Therapists will conduct individual therapy sessions with depressed adolescents using modules from the Coping with Stress manual. Social cognitive training will not be provided to teens in this condition.",[13],[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","The study has two intervention arms to which depressed adolescents will be randomized: (1) CBTSCT is cognitive behavioral therapy enhanced with training in social cognitive abilities (e.g., social perspective taking), and (2) CBT only is cognitive behavioral therapy without the additional social cognitive training component.",[15,9],[15],null,[27,32],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Judy Garber, PhD","CONTACT","615-330-5605","judy.garber@vanderbilt.edu",{"name":33,"role":29,"phone":34,"phoneExt":25,"email":35},"Steven D Hollon, PhD","615-373-2422","steven.d.hollon@vanderbilt.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Judy Garber","RECRUITING","Nashville","Tennessee","37203-5721","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-86.78444,36.16589,{"lat":49,"lon":48},[52,55,57,59],{"name":28,"role":29,"phone":53,"phoneExt":25,"email":54},"615-343-8714","jgarber.vanderbilt@gmail.com",{"name":33,"role":29,"phone":56,"phoneExt":25,"email":35},"615-322-3369",{"name":28,"role":58,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"name":33,"role":58,"phone":25,"phoneExt":25,"email":25},{"type":58,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Judith Garber","Professor of Psychology and Human Development",[64],{"name":65,"class":66},"National Institute of Mental Health (NIMH)","NIH","100474294","cbt-enhanced-with-social-cognitive-training-vs-cbt-only-with-depressed-youth-100474294",false,"NCT05456035","CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth","Social Cognitive Training to Enhance the Efficacy of CBT forDepression in Youth: A Developmental Approach (R33)","Inclusion Criteria:\n\n1. Participants ages 13- through 17-years-old\n2. Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) \\> 15\n\nExclusion Criteria:\n\n* ever met criteria for a diagnosis of bipolar disorder, schizophrenia, autism, or conduct disorder\n* current alcohol or substance use disorder with significant impairment\n* imminent risk of suicide\n* reading level \\\u003C 4th grade","ALL","13 Years","17 Years",{"count":78,"type":79},82,"ESTIMATED","INTERVENTIONAL",[82],"NA","Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.",[85],"Depression",[85,87,88],"Adolescents","Cognitive behavior therapy","2025-09-02",{"date":91,"type":92},"2025-09-09","ACTUAL",{"date":94,"type":92},"2022-10-10",{"date":96,"type":79},"2026-08",{"name":5,"class":6},1]