[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100213878":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":25,"responsibleParty":62,"collaborators":65,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":10,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Infants with a first-degree relative with celiac disease",null,"Infants who have a first-degree relative diagnosed with celiac disease.",[13,16],{"name":14,"affiliation":5,"role":15},"Alessio Fasano, MD","PRINCIPAL_INVESTIGATOR",{"name":17,"affiliation":5,"role":18},"Maureen M. Leonard, MD","STUDY_CHAIR",[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Victoria Kenyon, MHA","CONTACT","617-643-4366","vakenyon@mgb.org",[26,45],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"MassGeneral Hospital for Children","RECRUITING","Boston","Massachusetts","02114","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-71.05977,42.35843,{"lat":38,"lon":37},[41,42,43],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":14,"role":15,"phone":10,"phoneExt":10,"email":10},{"name":17,"role":44,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"facility":46,"status":28,"city":47,"state":10,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"University of Roma La Sapienza","Rome","00185","Italy","IT",{"type":35,"coordinates":52},[53,54],12.51133,41.89193,{"lat":54,"lon":53},[57,60],{"name":58,"role":22,"phone":10,"phoneExt":10,"email":59},"Francesco Valitutti, MD","cdgemmita@mgh.harvard.edu",{"name":61,"role":15,"phone":10,"phoneExt":10,"email":10},"Salvatore Cucchiara, MD PhD",{"type":15,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Alessio Fasano","Chief of Pediatric Gastroenterology and Nutrition",[66,67],{"name":46,"class":6},{"name":68,"class":6},"Università Politecnica delle Marche","100213878","celiac-disease-genomic-environmental-microbiome-and-metabolomic-study-100213878",false,"NCT02061306","Celiac Disease Genomic Environmental Microbiome and Metabolomic Study","Celiac Disease Genomic Environmental Microbiome and Metabolomic (CDGEMM) Study","CDGEMM","Inclusion Criteria:\n\n* Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)\n* First-degree relatives of patients affected with biopsy-proven CD\n\nExclusion Criteria:\n\n* Infants older than 6 months of age\n* Inability or unwillingness of legal guardian\u002Frepresentative to give written informed consent","ALL","6 Months",{"count":80,"type":81},500,"ESTIMATED","OBSERVATIONAL","Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.",[85],"Celiac Disease",[87,88,89,90,91,92,93],"Celiac disease","coeliac disease","microbiome","gluten","infants","pregnancy","genetic","2026-04-14",{"date":96,"type":97},"2026-04-17","ACTUAL",{"date":99,"type":10},"2014-03",{"date":101,"type":81},"2027-12",{"name":5,"class":6},2]