[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616383":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":18,"responsibleParty":25,"collaborators":29,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":18,"eligibilityCriteria":38,"healthyVolunteers":39,"sex":40,"minAge":41,"maxAge":18,"enrollmentInfo":42,"targetDuration":18,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":53,"whyStopped":18,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":18},{"fullName":5,"class":6},"Oregon Health and Science University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Center M","EXPERIMENTAL","In addition to standard prenatal care, participants will participate in Center M sessions, which are weekly one-hour digital group sessions led by a therapist. Each group will include 3-6 participants. The Center M session structure aligns with mindfulness-based cognitive therapy by including mental well-being, core mindfulness and cognitive behavioral therapy skills, in-session practice of skills, and home practice skills. Center M content teaches skills that increase capability for effectively navigating general life stress and the unique stresses of pregnancy and parenting.",[13],"Behavioral: Center M",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment as Usual (TAU)","NO_INTERVENTION","Those randomized to TAU will receive prenatal care as it is standardly delivered in their provider's clinical setting, including perinatal screenings and related educational handouts. Participants will be able to engage in any services recommended by their primary prenatal provider or that they voluntarily initiate, including mental health treatment. Participants will not be proscribed from engaging in other recommended interventions or care.",null,[20],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL",[9],[24],"Mindfulness Based Cognitive Therapy - Perinatal Depression",{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Ellen Tilden","Principal Investigator",[30],{"name":31,"class":32},"John & Tami Marick Foundation","UNKNOWN","100616383","center-m-randomized-trial-100616383",false,"NCT07304895","Center M Randomized Trial","Inclusion Criteria:\n\n* Currently pregnant at ≥ 12 weeks of gestation age (GA)\n* ≤ 34 weeks GA at time of Center M intervention initiation\n* Receiving prenatal care through the Center for Women's Health at Oregon Health \\& Science University\n* Able to fluently understand, speak and read English\n* Available, able and willing to attend online group sessions\n* Willing and able to receive home practice materials on an accessible smartphone, tablet or computer\n* Residing in Oregon or Washington\n* Willingness to participate in either randomization arm\n\nExclusion Criteria:\n\n* Current or past enrollment in a formal mindfulness-based intervention group\n* Score in the \"severe\" range on the Edinburgh Postnatal Depression Scale (EPDS) (≥ 20) or Patient History Questionnaire (PHQ-9) (≥ 20)",true,"FEMALE","18 Years",{"count":43,"type":44},160,"ESTIMATED","INTERVENTIONAL",[47],"NA","This is a randomized controlled trial with an intervention of Center M compared to treatment as usual. Center M consists of weekly digital one-hour group sessions led by a trained therapist aligned with mindfulness based cognitive therapy. Changes in perinatal depression symptoms will be compared between groups.",[50],"Perinatal Depression",[52],"mindfulness based cognitive therapy","NOT_YET_RECRUITING","2025-12-11",{"date":56,"type":57},"2025-12-26","ACTUAL",{"date":59,"type":44},"2025-12",{"date":61,"type":44},"2026-12",{"name":5,"class":6}]