[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617261":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":54,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":79,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Inonu University","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Painful DPN Group",null,"The study will include individuals aged 18-80 years who have been diagnosed with diabetic neuropathy, show a positive result on the MNSI-clinical assessment, and have a DN4 score of ≥4.This study is entirely observational and cross-sectional in nature, and no therapeutic intervention will be administered to the participants.",{"label":13,"type":10,"description":14,"interventionNames":10},"Painless DPN Group","The study will include individuals aged 18-80 years who have been diagnosed with diabetes mellitus, have a positive MNSI-clinical assessment, and a DN4 score of \\\u003C4. This study is entirely observational and cross-sectional in nature, and no therapeutic intervention will be administered to the participants.",{"label":16,"type":10,"description":17,"interventionNames":10},"Diabetic Control Group Without Diabetic Peripheral Neuropathy (DPN)","The study will include individuals aged 18-80 years who have been diagnosed with diabetes mellitus, have a negative MNSI-clinical assessment, and a DN4 score of \\\u003C4. This study is entirely observational and cross-sectional in nature, and no therapeutic intervention will be administered to the participants.",{"label":19,"type":10,"description":20,"interventionNames":10},"Healthy Control Group","The study will include individuals aged 18-80 years who do not have a diagnosis of diabetes mellitus, have a negative MNSI-clinical assessment, and a DN4 score of \\\u003C4. This study is entirely observational and cross-sectional in nature, and no therapeutic intervention will be administered to the participants.",[22],{"name":23,"affiliation":5,"role":24},"Zeynal Yasacı","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Gamze Levent","CONTACT","+905455169598","uzunhasanoglugamze@gmail.com",{"name":23,"role":28,"phone":32,"phoneExt":10,"email":33},"+905075409791","zeynal.yasaci@inonu.edu.tr",[35],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"countryCode":10,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Inonu University Turgut Ozal Medical Center, Malatya","Malatya","Turkey (Türkiye)",{"type":40,"coordinates":41},"Point",[42,43],38.31667,38.35018,{"lat":43,"lon":42},[46,50,53],{"name":47,"role":28,"phone":48,"phoneExt":10,"email":49},"Inonu University Turgut Ozal Medical Center","+904223410660","totm@inonu.edu.tr",{"name":51,"role":28,"phone":52,"phoneExt":10,"email":10},"Funda Datlı Yakaryılmaz","+905057805503",{"name":27,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":24,"investigatorFullName":23,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Doctor Lecturer","100617261","central-sensitization-in-painful-and-painless-diabetic-peripheral-neuropathy-100617261",false,"NCT07316322","Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy","Comparison of Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy Phenotypes: A Multidimensional Psychophysiological Assessment","Inclusion Criteria:\n\n* Being between 18 and 80 years of age\n* Having a diagnosis of Type 2 diabetes mellitus for at least 1 year\n* Providing written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Non-diabetic causes of polyneuropathy (alcohol, chemotherapy, vitamin deficiencies, renal failure, hypothyroidism, etc.)\n* Active ulcer, infection, or severe vascular insufficiency in the lower extremity\n* Central nervous system disorders (stroke, multiple sclerosis, spinal cord injury, etc.)\n* Skin lesions, dermatitis, wounds, or infection in the test areas (foot or forearm)\n* Peripheral entrapment neuropathies or related radiculopathies (e.g., carpal tunnel syndrome, C7-C8 radiculopathy)\n* Chronic widespread pain syndrome (fibromyalgia, etc.) or active flaring rheumatologic disease\n* Dose change within the last 2-4 weeks in medications affecting pain modulation (gabapentinoids, SNRI\u002FTCA, opioids, hypnotics, etc.)",true,"ALL","18 Years","80 Years",{"count":68,"type":69},128,"ESTIMATED","OBSERVATIONAL","This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy. The study will be conducted among individuals diagnosed with type 2 diabetes mellitus at the Department of Geriatrics, İnönü University Turgut Özal Medical Center. All assessments will be administered in accordance with a rigorously standardized protocol.\n\nEligible participants will include individuals aged 18 to 80 years who have had a confirmed diagnosis of type 2 diabetes mellitus for at least one year, are capable of comprehending and following verbal instructions in Turkish required for the study procedures, and provide written informed consent.\n\nAll statistical analyses will be performed using IBM SPSS Statistics (v.29, Armonk, NY, USA) and JASP (v.0.18, Amsterdam, Netherlands).",[73],"Diabetes Mellitus (DM)",[75,76,77,78],"Diabetus Mellitus","Central sensitization","Temporal summation","Neuropathic pain","NOT_YET_RECRUITING","2026-01-01",{"date":82,"type":83},"2026-01-05","ACTUAL",{"date":85,"type":69},"2025-12-15",{"date":87,"type":69},"2026-09-15",{"name":5,"class":6},1]