[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615381":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":39,"centralContacts":43,"locations":51,"responsibleParty":70,"collaborators":23,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":74,"sex":80,"minAge":81,"maxAge":23,"enrollmentInfo":82,"targetDuration":23,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":94,"overallStatus":54,"whyStopped":23,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"York Teaching Hospitals NHS Foundation Trust","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"LEFT internal jugular vein CVC with IC-ECG and thoracic POCUS","ACTIVE_COMPARATOR","LEFT internal jugular vein CVC with IC-ECG and thoracic POCUS. Post procedure chest x-ray.",[13,14],"Device: Intracavity ECG","Diagnostic Test: Thoracic point of care ultrasound",{"label":16,"type":10,"description":17,"interventionNames":18},"RIGHT internal jugular vein CVC with IC-ECG and thoracic POCUS","RIGHT internal jugular vein CVC with IC-ECG and thoracic POCUS. Post procedure chest x-ray.",[13,14],{"label":20,"type":21,"description":22,"interventionNames":23},"Standard care","NO_INTERVENTION","Left or right internal jugular vein CVC. Post procedure CXR.",null,[25,32],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Intracavity ECG","Vygon PILOT TLS (Tip Location System) used to provide intracavity ECG monitoring for central venous catheter tip positioning.",[9,16],[31],"IC-ECG",{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"DIAGNOSTIC_TEST","Thoracic point of care ultrasound","Thoracic point of care ultrasound used to scan both lung fields to rule out pneumothorax",[9,16],[38],"POCUS",[40],{"name":41,"affiliation":5,"role":42},"Andrew Chamberlain, MBChB","PRINCIPAL_INVESTIGATOR",[44,48],{"name":41,"role":45,"phone":46,"phoneExt":23,"email":47},"CONTACT","+441904 631313","andrew.chamberlain8@nhs.net",{"name":49,"role":45,"phone":46,"phoneExt":23,"email":50},"Joseph Carter, MBChB","joseph.carter4@nhs.net",[52],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"York and Scarborough Teaching Hospitals NHS Foundation Trust","RECRUITING","York","North Yorkshire","YO31 8HE","United Kingdom","UK",{"type":61,"coordinates":62},"Point",[63,64],-1.08271,53.95763,{"lat":64,"lon":63},[67,68,69],{"name":41,"role":45,"phone":46,"phoneExt":23,"email":47},{"name":49,"role":45,"phone":46,"phoneExt":23,"email":50},{"name":41,"role":42,"phone":23,"phoneExt":23,"email":23},{"type":71,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100615381","central-venous-catheter-placement-with-thoracic-ultrasound-and-intracavity-ecg-positioning-100615381",false,"NCT07291869","Central Venous Catheter Placement With Thoracic Ultrasound and Intracavity ECG Positioning","A Randomised Feasibility Study of Real-time Intracavity ECG and Thoracic Ultrasound for Central Venous Catheter Tip Confirmation in Critical Care","CVC-TIP","Inclusion Criteria:\n\n* Adult (aged ≥ 18 years)\n* Admitted, or planned for admission, to critical care\n* Requiring central venous catheter insertion as a part of their usual care\n* Suitable for both right or left internal jugular vein insertion\n\nExclusion Criteria:\n\n* Previously randomised into CVC-TIP\n* Atrial fibrillation on 12-lead ECG\n* Cardiovascular instability, defined as\n* Noradrenaline dose \\> 0.5mcg\u002Fkg\u002Fmin\n* Rapidly escalating doses of vasopressors \u002F inotropes\n* Difficulty in obtaining thoracic ultrasound images due to either\n* Weight \\> 120kg\n* Existing pneumothorax (either side)\n* Subcutaneous emphysema\n* Wounds \u002F dressing over anterior chest wall\n* Existing pacemaker\n* Non-English speaking participants\n* Death perceived as imminent\n* Any other reason as determined by treating clinician","ALL","18 Years",{"count":83,"type":84},75,"ESTIMATED","INTERVENTIONAL",[87],"NA","The goal of this interventional study is to assess the feasibility of two bedside techniques for confirming central venous catheter (CVC) placement and detecting complications:\n\n* Intracavity ECG monitoring to confirm internal jugular vein CVC tip position.\n* Thoracic point-of-care ultrasound (POCUS) to rule out pneumothorax following CVC insertion.\n\nParticipants who require an internal jugular CVC as part of their routine care and meet all inclusion and no exclusion criteria will be randomised to receive either:\n\n* Standard care, or\n* The intervention, consisting of intracavity ECG guidance and thoracic POCUS. The CVC will be inserted either on the left or right side of the neck.\n\nAll participants will undergo a post-procedure chest X-ray regardless of study arm, to allow comparison of the intervention methods with standard care.",[90,91,92,93],"Central Venous Catheter","Point of Care Ultrasound (POCUS)","Intracavitary Electrocardiogram Guiding","Feasibility Studies",[27,38,31,34],"2026-05-28",{"date":97,"type":98},"2026-06-02","ACTUAL",{"date":100,"type":98},"2026-05-15",{"date":102,"type":84},"2027-10",{"name":5,"class":6},1]