[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562189":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":28,"centralContacts":32,"locations":42,"responsibleParty":79,"collaborators":27,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":27,"enrollmentInfo":92,"targetDuration":27,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":27,"overallStatus":45,"whyStopped":27,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"tACS session 50 Hz","ACTIVE_COMPARATOR","Three single sessions of tACS, each lasting 20 minutes, will be conducted 7-15 days apart, with a different frequency (50 or 70 Hz, corresponding to gamma oscillations) or a placebo frequency known as \"sham.\"",[13],"Device: tACS Transcranial alternating stimulation",{"label":15,"type":10,"description":11,"interventionNames":16},"tACS session 70 Hz",[13],{"label":18,"type":19,"description":11,"interventionNames":20},"tACS Sham session","SHAM_COMPARATOR",[13],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","tACS Transcranial alternating stimulation","session of 20 minutes",[18,9,15],null,[29],{"name":30,"affiliation":5,"role":31},"Charlotte ROSSO, MD PHD","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":27,"email":37},"Charlotte ROSSO, MD PhD","CONTACT","+33142162103","charlotte.rosso@aphp.fr",{"name":39,"role":35,"phone":40,"phoneExt":27,"email":41},"Isabelle LOUBINOUX, PhD","+33562746183","isabelle.loubinoux@inserm.fr",[43,60],{"facility":44,"status":45,"city":46,"state":27,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"ICM_ Institut du Cerveau et de la Moelle épinière, Hôpital Pitié, 47 Bd de l'Hôpital","RECRUITING","Paris","75013","France","FR",{"type":51,"coordinates":52},"Point",[53,54],2.3488,48.85341,{"lat":54,"lon":53},[57],{"name":58,"role":35,"phone":59,"phoneExt":27,"email":37},"Charlotte MD ROSSO","+33 1 42 16 18 54",{"facility":61,"status":62,"city":63,"state":27,"zip":64,"country":48,"countryCode":49,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"ToNIC - Toulouse neuro Imaging center (Inserm)Pavillon Baudot","NOT_YET_RECRUITING","Toulouse","31300",{"type":51,"coordinates":66},[67,68],1.44367,43.60426,{"lat":68,"lon":67},[71,74,77],{"name":72,"role":35,"phone":73,"phoneExt":27,"email":41},"Isabelle LOUBINOUX","05.62.74.61.84",{"name":75,"role":76,"phone":27,"phoneExt":27,"email":27},"Phillippe MD MARQUE","SUB_INVESTIGATOR",{"name":78,"role":76,"phone":27,"phoneExt":27,"email":27},"Marianne MD BARBIEUX-GUILLOT",{"type":80,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100562189","cerebello-motor-neuromodulation-after-stroke-cerstim-100562189",false,"NCT06599931","Cerebello-motor Neuromodulation After Stroke. CERSTIM.","CEREBELLO-MOTOR NEUROMODULATION AFTER STROKE","CERSTIM","PATIENTS\n\nInclusion Criteria:\n\n* Male or female aged 18 years or older on the day of inclusion.\n* Affiliated with a social security system, Universal Health Coverage (CMU), or any equivalent scheme.\n* Ischemic stroke or intraparenchymal hematoma that occurred more than 6 months ago, with no upper time limit.\n* Motor deficit of the upper limb confirmed by the ARAT scale, with the ability to grip and press on a tablet.\n* stroke lesion not affecting the motor cortex in the hand knob area.\n\nExclusion Criteria:\n\n\\-- Pregnant and breastfeeding women\n\n* Total paralysis of the affected hand\n* Conditions that are life-threatening or could compromise follow-up during the study period\n* Contraindications to MRI and tACS (ferromagnetic surgical clips, ocular implants, intraocular or nervous system metallic foreign bodies, implants or metallic objects likely to concentrate the radiofrequency field, cochlear implants, brain or cardiac stimulators, presence of a craniotomy scar)\n* Participation in another biomedical study focused on motor or overall recovery during the same period, or current exclusion period from another biomedical study\n\nHEALTHY\n\nInclusion Criteria:\n\n* Male or female aged 18 years or older on the day of inclusion.\n* Affiliated with a social security system, Universal Health Coverage (CMU), or any equivalent scheme.\n\nNon inclusion criteria\n\n\\-- Pregnant and breastfeeding women\n\n* Conditions that are life-threatening or could compromise follow-up during the study period\n* Contraindications to MRI and tACS (ferromagnetic surgical clips, ocular implants, intraocular or nervous system metallic foreign bodies, implants or metallic objects likely to concentrate the radiofrequency field, cochlear implants, brain or cardiac stimulators, presence of a craniotomy scar)\n* Participation in another biomedical study during the same period, or current exclusion period from another biomedical study",true,"ALL","18 Years",{"count":93,"type":94},45,"ESTIMATED","INTERVENTIONAL",[97],"NA","The CERSTIM study is a physiopatholgical study investigating transcranial alternating current stimulation in stroke patients in the cerebello-motor loop.\n\nThe design is a cross over design testing two frequencies in the gamma band and one placebo.\n\nWe will use behavioural data, functional MRI, and Electroencephalography to disentangle the effect of tACS and its frequency.\n\nHealthy participants will be also recruited.",[100,101],"Stroke","Healthy","2026-04-13",{"date":104,"type":105},"2026-04-16","ACTUAL",{"date":107,"type":105},"2024-12-13",{"date":109,"type":94},"2027-12-30",{"name":5,"class":6},2]