[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100469710":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":59,"collaborators":61,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":35,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":35,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":35,"overallStatus":42,"whyStopped":35,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"American University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Right cerebellum","EXPERIMENTAL","Participants (neurotypical, autistic) in this arm will receive tDCS targeting the right posterolateral cerebellum (lobule VII). All participants will receive anodal, cathodal and sham tDCS.",[13],"Device: Transcranial direct current stimulation",{"label":15,"type":10,"description":16,"interventionNames":17},"Posterior vermis","Participants (neurotypical, autistic) in this arm will receive tDCS targeting the posterior cerebellar vermis. All participants will receive anodal, cathodal and sham tDCS.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Transcranial direct current stimulation","TDCS involves applying small (1-2 mA) electric currents to the scalp in order to transiently modify local neuronal electrical potentials in the brain.",[15,9],[25],"tDCS",[27],{"name":28,"affiliation":5,"role":29},"Kathleen Gunthert, Ph.D.","PRINCIPAL_INVESTIGATOR",[31,37],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Catherine Stoodley, D.Phil.","CONTACT","202-476-4799",null,"stoodley@american.edu",{"name":38,"role":33,"phone":35,"phoneExt":35,"email":39},"Joe Dust, M.Sc.","jd7958a@american.edu",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Washington D.C.","District of Columbia","20016","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-77.03637,38.89511,{"lat":52,"lon":51},[55,57],{"name":32,"role":33,"phone":56,"phoneExt":35,"email":36},"202-885-1785",{"name":58,"role":29,"phone":35,"phoneExt":35,"email":35},"Catherine Stoodley",{"type":29,"investigatorFullName":58,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"Associate Professor",[62,65],{"name":63,"class":64},"National Institutes of Health (NIH)","NIH",{"name":66,"class":64},"National Institute of Mental Health (NIMH)","100469710","cerebellum-and-autism-regional-specialization-for-social-and-executive-functions-100469710",false,"NCT05396352","Cerebellum and Autism: Regional Specialization for Social and Executive Functions","Please note: This study takes place at American University and Georgetown University in Washington, DC. We do not have funds for travel and lodging available for this study, so participants should be local to the DC region.\n\nInclusion Criteria:\n\nAll participants\n\n* Aged 18-35\n* Able to provide written, informed consent\n* NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85\n* Native English speaker\n* Right-handed\n* Not pregnant\n* Able to attend all study sessions\n* Pass safety screening for MRI and neuromodulation (e.g. no metal in body, implanted devices, history of seizure, claustrophobia)\n\nAdditional INCLUSION criteria for adults with autism Either\n\n* Prior research-reliable diagnosis of autism spectrum disorder (ASD) Or\n* Meet DSM-5 criteria for ASD confirmed with ADOS-2 via research-reliable clinical assessment\n\nExclusion Criteria:\n\nNeurotypical adults\n\n* Age \\\u003C18 or \\>35\n* NIH Toolbox age-adjusted Cognitive Function Composite standard score \\\u003C 85\n* Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)\n* Current or prior history of neurological or neurodevelopmental condition or brain injury\n* Psychotropic medication\n* Pregnancy\n\nAdults with autism\n\n* Age \\\u003C18 or \\>35\n* Participants with a legal authorized representative\n* NIH Toolbox age-adjusted Cognitive Function Composite standard score \\\u003C 85\n* Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)\n* Pregnancy",true,"ALL","18 Years","35 Years",{"count":78,"type":79},80,"ESTIMATED","INTERVENTIONAL",[82],"NA","The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.",[85,86],"Autism","Autism Spectrum Disorder","2025-09-29",{"date":89,"type":90},"2025-10-02","ACTUAL",{"date":92,"type":90},"2022-01-01",{"date":94,"type":79},"2025-12-31",{"name":5,"class":6},1]