[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552989":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":60,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":26,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":85,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Papa Giovanni XXIII Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Helmet","EXPERIMENTAL","Partecipants will be started on Continuous Positive Airway Pressure using the Helmet interface",[13],"Device: Helmet Continuous Positive Airway Pressure",{"label":15,"type":16,"description":17,"interventionNames":18},"Oronasal Mask","ACTIVE_COMPARATOR","Partecipants will be started on Continuous Positive Airway Pressure using the oronasal mask interface",[19],"Device: Oronasal Mask Continuous Positive Airway Pressure",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Helmet Continuous Positive Airway Pressure","Partecipants will be started on Continuous Positive Airway Pressure at 10 cmH2O on inspired fraction of oxygen (FiO2)= 21% with the Helmet interface for a duration of 5 minutes while laying down on a stretcher with head elevated at 60°",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Oronasal Mask Continuous Positive Airway Pressure","Partecipants will be started on Continuous Positive Airway Pressure at 10 cmH2O on Inspired fraction of oxygen (FiO2)= 21% with the oronasal mask interface for a duration of 5 minutes while laying down on a stretcher with head elevated at 60°",[15],[32],{"name":33,"affiliation":34,"role":35},"Roberto Cosentini, MD","Ospedale Papa Giovanni XXIII","STUDY_DIRECTOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Andrea Duca, MD","CONTACT","+393396980738","a.duca85@gmail.com",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},"+390352678981","r.cosentini@asst-pg23.it",[46],{"facility":34,"status":26,"city":47,"state":26,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Bergamo","24127","Italy","IT",{"type":52,"coordinates":53},"Point",[54,55],9.66721,45.69601,{"lat":55,"lon":54},[58],{"name":33,"role":39,"phone":43,"phoneExt":26,"email":59},"rcosentini@asst-pg23.it",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Roberto Cosentini","Director of Emergency Department","100552989","cerebral-blood-flow-helmet-vs-oronasal-mask-during-continuous-positive-airway-pressure-ventilation-100552989",false,"NCT06480253","Cerebral Blood Flow: Helmet vs Oronasal Mask During Continuous Positive Airway Pressure Ventilation","Variation of Cerebral Blood Flow Depending on the Interface Chosen During Continuous Positive Airway Pressure Ventilation","Inclusion Criteria:\n\n* Age ≥ 18 years,\n* Ability to give informed consent\n\nExclusion Criteria:\n\n* known cardiac pathologies\n* known pulmonary pathologies\n* known vascular pathologies\n* history of concussion\n* history of headache",true,"ALL","18 Years",{"count":75,"type":76},19,"ESTIMATED","INTERVENTIONAL",[79],"NA","In this trial the investigators will evaluate blood flow in common carotid artery of healthy subjects treated with Continuous Positive Airway Pressure (CPAP) Ventilation, comparing two different devices: oronasal mask versus Helmet. The hypothesis is that Helmet CPAP reduces carotid flow compared to oronasal mask.",[82],"Ventilation Therapy",[84],"Continuous Positive Airway Pressure","NOT_YET_RECRUITING","2024-06-24",{"date":88,"type":89},"2024-06-28","ACTUAL",{"date":91,"type":76},"2024-07-01",{"date":93,"type":76},"2024-07-31",{"name":5,"class":6},1]