[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625800":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":40,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":63,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Term Neonates",null,"Normal Term neonates ≥ 37 weeks of gestational age",{"label":13,"type":10,"description":14,"interventionNames":10},"Preterm Neonates","Normal Preterm neonates \\\u003C 37 weeks' gestational age",[16],{"name":17,"affiliation":5,"role":18},"Hisham Mostafa Kamel, Professor","STUDY_DIRECTOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Sawsan Samy Aly Aly","CONTACT","01159860374","Sawsan.15235540@med.aun.edu.eg",{"name":26,"role":22,"phone":10,"phoneExt":10,"email":27},"Mostafa Ahmed Sayed, Lecturer","most.rad@aun.edu.eg",[29],{"facility":30,"status":10,"city":31,"state":10,"zip":10,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":10},"Assiut university","Asyut","Egypt","EG",{"type":35,"coordinates":36},"Point",[37,38],31.18368,27.18096,{"lat":38,"lon":37},{"type":41,"investigatorFullName":21,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Resident doctor","100625800","cerebral-blood-flow-in-term-and-preterm-neonates-using-doppler-ultrasonography-100625800",false,"NCT07427342","Cerebral Blood Flow in Term and Preterm Neonates Using Doppler Ultrasonography","Comparative Analysis of Cerebral Blood Flow in Term and Preterm Neonates Using Doppler Ultrasonography","Inclusion Criteria:\n\n* Term neonates ≥ 37 weeks of gestational age.\n* Preterm neonates \\\u003C 37 weeks' gestational age.\n* Hemodynamically stable infants at the time of examination.\n* Parental\u002Fguardian informed consent obtained.\n* Within the first 48 hours after birth.\n* Birth weight appreciate for gestational age.\n\nExclusion Criteria:\n\n* Infants aged more than 48 hours after birth.\n* Neonates with major congenital anomalies (cardiac, neurological, or craniofacial).\n* Suspected or confirmed intracranial hemorrhage or brain malformations, such as intraventricular hemorrhage, may influence RI measurements and interfere with accurate assessment of cerebral blood flow.\n* Neonates requiring inotropic support at the time of scan.\n* Neonates with severe respiratory instability or mechanical ventilation (unless included intentionally).\n* Infants with sepsis or metabolic derangements affecting cerebral perfusion.","ALL","1 Hour","48 Hours",{"count":54,"type":55},200,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate cerebral blood flow in stable term and preterm newborns using Doppler ultrasonography. By measuring and comparing PSV, EDV, RI, and PI in the main brain arteries, the study seeks to identify normal physiological differences in cerebral perfusion across different gestational ages. The main goal is to establish reference values that can guide clinical monitoring, allow early detection of blood flow problems, and improve neuroprotective care in newborns.",[59],"Cerebral Blood Flow",[59,61,62],"Doppler Ultrasonography","Term and Preterm Neonates","NOT_YET_RECRUITING","2026-02-17",{"date":66,"type":67},"2026-02-23","ACTUAL",{"date":69,"type":55},"2026-04-15",{"date":71,"type":55},"2027-12-15",{"name":5,"class":6},1]