[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639354":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":33,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Centre Paul Strauss","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients with glioblastoma treated in the Department of Nuclear Medicine & Molecular Imaging",null,[12],"Other: 18F-FDG PET\u002FMRI with additional DTI and rs-fMRI sequences",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"18F-FDG PET\u002FMRI with additional DTI and rs-fMRI sequences","fluorodeoxyglucose (Fluor18) (18F-FDG) PET\u002FMRI with additional DTI and rs-fMRI sequences correlation with neuropsychological tests",[9],[19],{"name":20,"affiliation":21,"role":22},"Izzie-Jacques NAMER, MD, PhD","Institut Public De Cancerologie Strauss Europe","PRINCIPAL_INVESTIGATOR",[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Claire VIT","CONTACT","(0)388258529","+33","promotion-rc@institut-strauss.fr",{"name":31,"role":26,"phone":32,"phoneExt":28,"email":29},"Manon VOEGELIN","(0)368339523",[34],{"facility":35,"status":10,"city":36,"state":10,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Institut public de cancérologie Strauss Europe","Strasbourg","67033","France","FR",{"type":41,"coordinates":42},"Point",[43,44],7.74553,48.58392,{"lat":44,"lon":43},[47,48,49],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},{"name":31,"role":26,"phone":32,"phoneExt":28,"email":29},{"name":20,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100639354","cerebral-connectivity-and-metabolic-phenotype-of-gliomas-prospective-addition-of-dti-and-rs-fmri-to-a-preoperative-fdg-pet-strategy-with-neuropsychological-correlates-and-post-treatment-follow-up-100639354",false,"NCT07628257","Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up","Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of Diffusion Tensor Imaging (DTI) and Resting State Functional MRI (Rs-fMRI) to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up","GlioConnect","Inclusion Criteria:\n\n* Adult patients\n* Patients with glioblastoma\n* Patients treated in the Nuclear Medicine \\& Molecular Imaging Department of the Strauss Institute for PET\u002FMRI scans for:\n\n  * Preoperative metabolic evaluation of a brain-expanding lesion\n\nExclusion Criteria:\n\n* Contraindications to MRI\n* Minor or incapacitated adult\n* Patient deprived of liberty\n* Patient under legal guardianship\n* Patient unable to consent\n* Pregnant or breastfeeding woman","ALL","18 Years",{"count":63,"type":64},80,"ESTIMATED","INTERVENTIONAL",[67],"NA","The aim of this study is to determine whether the diffuse cerebral metabolic disturbances observed in glioblastoma are exclusively linked to the direct and indirect effects of tumor infiltration (particularly structural disconnection), or whether they also reflect a more global alteration of neurometabolic and neurovascular coupling mechanisms.\n\nThis approach thus aims to better understand the pathophysiological basis of cognitive impairment in glioblastoma and to characterize the impact of the disease at the level of brain networks.",[70],"Glioblastoma","NOT_YET_RECRUITING","2026-06-03",{"date":74,"type":75},"2026-06-04","ACTUAL",{"date":77,"type":64},"2026-09-15",{"date":79,"type":64},"2030-09-15",{"name":5,"class":6},1]