[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590815":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":129,"collaborators":19,"id":132,"slug":133,"hasResults":134,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":134,"sex":139,"minAge":140,"maxAge":19,"enrollmentInfo":141,"targetDuration":19,"studyType":144,"phases":145,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":153,"whyStopped":19,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":163},{"fullName":5,"class":6},"Central Hospital, Nancy, France","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cerebral Near infrared spectroscopy (NIRSc) group","EXPERIMENTAL","The use of cerebral Near infrared spectroscopy to predict the neurological prognosis of patients treated for out-of-hospital cardiac arrest.",[13],"Other: Cerebral Near infrared spectroscopy (NIRSc).",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Cerebral Near infrared spectroscopy (NIRSc).","Continuous cerebral near-infrared spectroscopy (NIRSc) during resuscitation in a patient treated for out-of-hospital cardiac arrest (OHCA).",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Nicolas GIRERD, MD-PhD","CHRU de NANCY","STUDY_CHAIR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Deborah JAEGER, MD","CONTACT","+33 (0) 3 83 85 85 85","D.JAEGER@chru-nancy.fr",{"name":32,"role":28,"phone":29,"phoneExt":19,"email":33},"Tahar CHOUIHED, MD PHD","T.CHOUIHEDMAHJOUB@chru-nancy.fr",[35,54,69,82,98,114],{"facility":36,"status":19,"city":37,"state":19,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"CH Colmar- Urgences - SAMU-SMUR","Colmar","68000","France","FR",{"type":42,"coordinates":43},"Point",[44,45],7.35584,48.08078,{"lat":45,"lon":44},[48,52],{"name":49,"role":28,"phone":50,"phoneExt":19,"email":51},"Yannick GOTTWALLES, MD","+33 (0) 3 89 12 40 00","yannick.gottwalles@ch-colmar.fr",{"name":49,"role":53,"phone":19,"phoneExt":19,"email":19},"PRINCIPAL_INVESTIGATOR",{"facility":55,"status":19,"city":56,"state":19,"zip":57,"country":39,"countryCode":40,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"CHR Metz-Thionville - Mercy hospital -Urgences - SAMU-SMUR","Metz","5700",{"type":42,"coordinates":59},[60,61],6.17269,49.11911,{"lat":61,"lon":60},[64,68],{"name":65,"role":28,"phone":66,"phoneExt":19,"email":67},"Philippe Alarcon, MD","+33 (0) 3 87 55 31 31","philippe.alarcon@chr-metz-thionville.fr",{"name":65,"role":53,"phone":19,"phoneExt":19,"email":19},{"facility":70,"status":19,"city":71,"state":19,"zip":72,"country":39,"countryCode":40,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"CHRU NANCY - urgences SAMUR SMUR- Central hospital","Nancy","54000",{"type":42,"coordinates":74},[75,76],6.18496,48.68439,{"lat":76,"lon":75},[79,81],{"name":27,"role":28,"phone":80,"phoneExt":19,"email":30},"+33 (0)3 83 85 85 85",{"name":27,"role":53,"phone":19,"phoneExt":19,"email":19},{"facility":83,"status":19,"city":84,"state":19,"zip":85,"country":39,"countryCode":40,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"CHU Reims - ugences - SAMU-SMUR","Reims","51100",{"type":42,"coordinates":87},[88,89],4.02853,49.26526,{"lat":89,"lon":88},[92,96],{"name":93,"role":28,"phone":94,"phoneExt":19,"email":95},"Stéphane GENNAI, MD","+33 (0)3 26 78 78 78","sgennai@chu-reims.fr",{"name":97,"role":53,"phone":19,"phoneExt":19,"email":19},"Séphane GENNAI, MD",{"facility":99,"status":19,"city":100,"state":19,"zip":101,"country":39,"countryCode":40,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Hôpitaux universitaire de Strasbourg - Urgences - SAMU-SMUR","Strasbourg","67200",{"type":42,"coordinates":103},[104,105],7.74553,48.58392,{"lat":105,"lon":104},[108,112],{"name":109,"role":28,"phone":110,"phoneExt":19,"email":111},"Anne Weiss, MD","+33 (0)3 88 11 67 68","anne.weiss@chru-strasbourg.fr",{"name":113,"role":53,"phone":19,"phoneExt":19,"email":19},"Anne WEISS, MD",{"facility":115,"status":19,"city":116,"state":19,"zip":117,"country":39,"countryCode":40,"cosmosGeoPoint":118,"geoPoint":122,"contacts":123},"CHR Troyes- Urgences - SAMU-SMUR","Troyes","10000",{"type":42,"coordinates":119},[120,121],4.08524,48.30073,{"lat":121,"lon":120},[124,128],{"name":125,"role":28,"phone":126,"phoneExt":19,"email":127},"Alain HUGEROT, MD","+33 (3) 25 49 49 49","alain.hugerot@ch-troyes.fr",{"name":125,"role":53,"phone":19,"phoneExt":19,"email":19},{"type":53,"investigatorFullName":130,"investigatorTitle":131,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"JAEGER Deborah","Coordinating Investigator","100590815","cerebral-near-infrared-spectroscopy-in-out-of-hospital-cardiac-arrest-and-neurological-prognosis-100590815",false,"NCT06972329","Cerebral Near Infrared Spectroscopy in Out-of-Hospital Cardiac Arrest and Neurological Prognosis","NISOHCA","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Non-traumatic out-of-hospital cardiac arrest witnessed and managed by the mobile emergency unit (SMUR).\n\nExclusion Criteria:\n\n* Scalp\u002Fcranial or facial injury preventing the placement of electrodes for NIRS measurement.\n* Spontaneous cardiac activity upon the arrival of the SMUR.\n* Decision by the SMUR physician not to initiate specialized resuscitation.","ALL","18 Years",{"count":142,"type":143},542,"ESTIMATED","INTERVENTIONAL",[146],"NA","Out-of-hospital cardiac arrest (OHCA) prognosis remains poor : 7% of patients surviving without neurological impairment.\n\n65% of patients dying after hospital admission were neurologically impaired. When treating a patient with CA, neurological outcome remains extremely difficult to predict, especially in the pre-hospital setting. Practitioners have very little objective information to help them with neuropronostication.\n\nAlthough an EtCO2 level of \\\u003C 10 mmHg is associated with a poor neurological prognosis, European recommendations point out that this data alone is not currently sufficient to predict a patient's prognosis or to make a decision to stop resuscitation. Current recommendations do not suggest any other objective parameter during resuscitation for neuropronostication of patients with out-of-hospital cardiac arrest.\n\nCerebral tissue oxygen saturation (rSO2) is measured using the near infrared spectrometry (NIRS) technique. Cerebral NIRS (cNIRS) enables non-invasive measurement of changes in cerebral oximetry during the management of a cardiac arrest (CA).\n\nVarious clinical studies conducted over the last ten years have demonstrated that there is a probable link between cNIRS levels during resuscitation and return of spontaneous circulation (ROSC), but a clear threshold value has not been defined.\n\nThe aim of the NISOHCA study is to confirm that a 40% threshold of cNIRS in the pre-hospital setting for OHCA can specifically predict survival with good neurological outcome at D90 .",[149],"Out-of-hospital Cardiac Arrest (OHCA)",[151,152],"Out-of-hospital cardiac arrest","Cerebral Near infrared spectroscopy (NIRSc)","NOT_YET_RECRUITING","2025-05-12",{"date":156,"type":157},"2025-05-15","ACTUAL",{"date":159,"type":143},"2025-11",{"date":161,"type":143},"2028-02",{"name":5,"class":6},6]