[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609336":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":37,"locations":46,"responsibleParty":63,"collaborators":66,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":102,"whyStopped":25,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CHAMPION Intervention Arm","EXPERIMENTAL","mHealth app to track and promote PrEP adherence using motivational messages combined with computer-administered cognitive behavioral therapy for the full 6-month period.",[13],"Behavioral: CHAMPION Intervention",{"label":15,"type":6,"description":16,"interventionNames":17},"Waitlist Control Arm","3-month waitlist period including informational resources, followed by 3-month CHAMPION intervention.",[18],"Behavioral: Delayed CHAMPION Package",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","CHAMPION Intervention","MHealth intervention to enhance PrEP adherence, combined with computer-administered cognitive behavioral therapy for a 6-month period for the intervention arm.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Delayed CHAMPION Package","Informational resources for first 3-months of study, followed by CHAMPION intervention for final 3-months.",[15],[31,35],{"name":32,"affiliation":33,"role":34},"Glenn-Milo Santos, PhD, MPH","University of California, San Francisco","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":5,"role":34},"Kiyomi Tsuyuki, PhD, MPH",[38,42],{"name":32,"role":39,"phone":40,"phoneExt":25,"email":41},"CONTACT","628-217-6231","glenn-milo.santos@ucsf.edu",{"name":43,"role":39,"phone":44,"phoneExt":25,"email":45},"Alexandrea Dunham, B.A.","530-925-3398","allie.dunham@sfdph.org",[47],{"facility":48,"status":25,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Center on Substance Use and Health","San Francisco","California","94102","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-122.41942,37.77493,{"lat":58,"lon":57},[61],{"name":62,"role":39,"phone":25,"phoneExt":25,"email":25},"Glenn-Milo Santos",{"type":34,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":33,"oldNameTitle":25,"oldOrganization":25},"Kiyomi Tsuyuki","Multi-Principal Investigator",[67,70],{"name":68,"class":69},"National Institute on Drug Abuse (NIDA)","NIH",{"name":33,"class":6},"100609336","champion-combining-hiv-and-meth-prevention-and-treatment-interventions-optimized-for-hiv-negative-msm-100609336",false,"NCT07213258","CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM","CHAMPION","Inclusion Criteria:\n\n1. HIV-negative\n2. Cis-gender male\n3. Age 18-40 years old\n4. Mild or moderate MUD (by DSM-5 SCID criteria)\n5. Anal intercourse with one or more male partners in the past 6 months\n6. Started daily oral PrEP more than 30 days ago and self-reported not always taking PrEP as prescribed in the past 30 days (consistent with PrEP It! inclusion criteria)\n7. Willingness to participate in an mHealth study with a 6-month follow-up\n8. Residing in San Diego or San Francisco County\n\nExclusion Criteria:\n\n1. Residing outside of San Diego or San Francisco County\n2. Any condition that, in the principal investigator's judgment interferes with safe study participation or adherence to study procedures\n3. Not able\u002Fwilling to complete virtual\u002Fremote visits\n4. Not willing to learn to self-collect dried blood spots using a finger stick","MALE","18 Years","40 Years",{"count":82,"type":83},100,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use disorder (MUD). The CHAMPION intervention combines two mHealth tools-PrEPAPP and CBT4CBT-to address both HIV prevention and MUD treatment needs in this population. The study's specific aims are:\n\n* To evaluate the feasibility and acceptability of the CHAMPION intervention based on treatment retention and engagement rates.\n* To examine the preliminary efficacy the CHAMPION intervention to improve PrEP adherence, as measured by dried blood spot (DBS) tests compared to the waitlist control group.",[89,90,91],"PrEP Adherence","Methamphetamine Use Disorder","HIV",[93,94,95,96,97,98,99,100,101],"MSM","HIV Negative","mild MUD","moderate MUD","Methamphetamine Use Disorder (MUD)","CBT4CBT","PrEPAPP","mHealth","Cognitive Behavioral Therapy","NOT_YET_RECRUITING","2025-10-07",{"date":105,"type":106},"2025-10-08","ACTUAL",{"date":108,"type":83},"2025-10-22",{"date":110,"type":83},"2026-08-15",{"name":5,"class":6},1]