[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515745":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":36,"centralContacts":41,"locations":49,"responsibleParty":71,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":25,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":25,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":25,"overallStatus":52,"whyStopped":25,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants with Bulimia Nervosa","EXPERIMENTAL","Participants are randomly assigned (in even numbers across the two groups) to scan order:\n\nA. These participants are first scanned after 16 hours of fasting on one day, and are next scanned after a standardized meal on a second day.\n\nB. These participants are first scanned after a standardized meal on one day, and are next scanned after 16 hours of fasting on a second day.",[13,14,15],"Other: Fasting state","Other: Fed state","Other: Magnetic Resonance Imaging",{"label":17,"type":18,"description":11,"interventionNames":19},"Participants without Bulimia Nervosa","ACTIVE_COMPARATOR",[13,14,15],[21,26,30],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Fasting state","16 hours of fasting",[9,17],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Fed state","Fed a standardized meal",[9,17],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Magnetic Resonance Imaging","Neuroimaging with computational modeling",[9,17],[35],"MRI",[37],{"name":38,"affiliation":39,"role":40},"Laura A Berner, Ph.D.","Mount Sinai Icahn School of Medicine","PRINCIPAL_INVESTIGATOR",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":25,"email":46},"Riley Macks, B.A.","CONTACT","(212) 824-9545","riley.macks@mssm.edu",{"name":48,"role":44,"phone":45,"phoneExt":25,"email":46},"Riley Macks",[50],{"facility":51,"status":52,"city":53,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai","RECRUITING","New York","10029","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-74.00597,40.71427,{"lat":61,"lon":60},[64,68,69],{"name":65,"role":44,"phone":66,"phoneExt":25,"email":67},"Jiulin Dai, B.S.","212-824-9561","jiulin.dai@mssm.edu",{"name":48,"role":44,"phone":45,"phoneExt":25,"email":46},{"name":70,"role":40,"phone":25,"phoneExt":25,"email":25},"Laura A Berner",{"type":40,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Laura Berner","Assistant Professor",[75],{"name":76,"class":77},"National Institute of Mental Health (NIMH)","NIH","100515745","changes-in-inhibition-and-valuation-after-eating-100515745",false,"NCT05995496","Changes in Inhibition and Valuation After Eating","Dynamic Neural Computations Underlying Cognitive Control in Bulimia Nervosa","Inclusion Criteria:\n\n* Female\n* Aged 18 to 45 years\n* Current BMI greater than or equal to 18.5kg\u002Fm2 but under 30kg\u002Fm2\n* Right-handed\n* English-speaking\n\nAdditional Inclusion Criteria for Women with Bulimia Nervosa:\n\n* Meet DSM-5 criteria for bulimia nervosa\n\nExclusion Criteria:\n\n* Medical instability\n* Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation\n* Shift work\n* Pregnancy, planned pregnancy, or lactation during the study period\n* Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period\n* Any contraindication for fMRI",true,"FEMALE","18 Years","45 Years",{"count":90,"type":91},150,"ESTIMATED","INTERVENTIONAL",[94],"NA","An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.",[97],"Bulimia Nervosa","2026-02-13",{"date":100,"type":101},"2026-02-17","ACTUAL",{"date":103,"type":101},"2023-12-12",{"date":105,"type":91},"2027-12-31",{"name":5,"class":6},1]