[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544678":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":36,"responsibleParty":53,"collaborators":56,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":10,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group - Nutritional Approach",null,"Patients who, after a multidisciplinary visit, are found to be ineligible for bariatric surgery.",[13],"Other: Nutritional Approach",{"label":15,"type":10,"description":16,"interventionNames":17},"Case group - Surgery Approach","Patients who, after a multidisciplinary visit, are referred for bariatric surgery.",[18],"Other: Surgery Approach",[20,23],{"type":6,"name":21,"description":21,"armGroupLabels":22,"otherNames":10},"Nutritional Approach",[9],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Surgery Approach","Bariatric surgery",[15],[28],{"name":29,"affiliation":5,"role":30},"Rossella Donghia, Biologyst","PRINCIPAL_INVESTIGATOR",[32],{"name":29,"role":33,"phone":34,"phoneExt":10,"email":35},"CONTACT","0804994652","rossella.donghia@irccsdebellis.it",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"IRCCS \"Saverio de Bellis\"","RECRUITING","Castellana Grotte","Bari","70013","Italy","IT",{"type":46,"coordinates":47},"Point",[48,49],17.16549,40.88643,{"lat":49,"lon":48},[52],{"name":29,"role":33,"phone":34,"phoneExt":10,"email":35},{"type":30,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Dr. Rossella Donghia","Biologyst",[57,60,62,64,66],{"name":58,"class":59},"Notarnicola Maria","UNKNOWN",{"name":61,"class":59},"Cozzolongo Raffaele",{"name":63,"class":59},"Shahini Endrit",{"name":65,"class":59},"De Pergola Giovanni",{"name":67,"class":59},"Lippolis Giuseppe","100544678","changes-in-the-lipidomic-immunological-and-mirna-profile-in-patients-undergoing-a-dietary-program-or-bariatric-surgery-100544678",false,"NCT06372015","Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery","Changes in the Lipidomic, Immunological and Circulating microRNA Profile in Patients With Hepatobiliary Pathology, Suffering From Morbid Obesity Undergoing a Dietary Program or Bariatric Surgery","Inclusion Criteria:\n\n* Obese patients (BMI \\>30kg\u002Fm2) suffering from hepato-biliary pathology diagnosed by Fibroscan\n* Adult patients (\\>18 years).\n\nExclusion Criteria:\n\n* Patients who are not obese or not affected by hepato-biliary pathology","ALL","18 Years",{"count":78,"type":79},60,"ESTIMATED","OBSERVATIONAL","Obesity is a chronic disease characterized phenotypically by an increase in body weight (BMI\\>30 kg\u002Fm2) and by a series of associated pathologies, such as hypertension, diabetes, hepatic steatosis.\n\nThe association of these pathologies compromises the patient's survival and quality of life. The multifactorial origin of obesity makes its etiopathology difficult to manage. It is often possible to follow only one therapeutic strategy, especially after the so-called standard treatments, such as dietary intervention and physical activity, have not brought benefit to the patient. In these cases, an appropriate treatment for the patient to enjoy significant weight loss is bariatric surgery.\n\nBariatric surgery refers to all those interventions aimed at reducing weight in those suffering from obesity, and treating the diseases associated with it.\n\nAmong the different types of bariatric surgery, the techniques most used in common clinical practice are intragastric balloons, gastric by pass (RYGB) and sleeve gastrectomy.\n\nThe choice of the surgeon, assisted by the multidisciplinary team, is binding in the choice of the type of operation to which the patient will be subjected.",[83,84],"Obesity","Liver Disease Parenchymal",[83,86,87],"Liver Diseases","Bariatric Surgery","2025-04-02",{"date":90,"type":91},"2025-04-04","ACTUAL",{"date":93,"type":91},"2024-06-01",{"date":95,"type":79},"2026-06-01",{"name":5,"class":6},1]