[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100145625":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":26,"locations":35,"responsibleParty":53,"collaborators":56,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":10,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of California, Irvine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Muscle weakness",null,"Diffuse Optical Spectroscopy",[13],"Device: Diffuse Optical Spectroscopy",[15],{"type":16,"name":11,"description":11,"armGroupLabels":17,"otherNames":10},"DEVICE",[9],[19,23],{"name":20,"affiliation":21,"role":22},"Virginia Kimonis, MD","Beckman Laser Institute University of California Irvine","PRINCIPAL_INVESTIGATOR",{"name":24,"affiliation":21,"role":25},"Bruce Tromberg, PhD","STUDY_DIRECTOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Marie Wencel, BS","CONTACT","949-824-0521","mwencel@uci.edu",{"name":20,"role":29,"phone":33,"phoneExt":10,"email":34},"714-456-5791","vkimonis@hs.uci.edu",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Hewitt Hall","RECRUITING","Irvine","California","92697","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-117.82311,33.66946,{"lat":48,"lon":47},[51],{"name":20,"role":29,"phone":52,"phoneExt":10,"email":34},"714-456-5792",{"type":22,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Virginia Kimonis","Virginia Kimonis, MD, MRCP",[57],{"name":21,"class":6},"100145625","characterization-of-familial-myopathy-and-paget-disease-of-bone-100145625",false,"NCT01166854","Characterization of Familial Myopathy and Paget Disease of Bone","Inclusion Criteria: Male or Female age 18 and older\n\n* diagnose of Muscle or bone disorders\n* with a combination of medical problems including muscle and bone disease and their family members.\n\nExclusion Criteria:\n\n* under 18 year of age\n* unrelated diagnosis","ALL","18 Years",{"count":67,"type":68},25,"ESTIMATED","OBSERVATIONAL","The researcher wants to explore the genetic causes of muscle disease. The researcher is particularly interested in muscle disorders that occur in combination with diseases of bone that appear to be passed on from generation to generation.\n\nDiffuse Optical Spectroscopy will measure the concentrations of blood, water, and lipids (fats, for example) in your tissues. This device essentially measures the color of tissues in order to determine tissue physiology (its physical and chemical processes).",[72,73],"Muscle Disorder","Bone Disorder",[75],"muscle and bone disease","2025-06-13",{"date":78,"type":79},"2025-06-18","ACTUAL",{"date":81,"type":79},"2010-06-18",{"date":83,"type":68},"2030-06",{"name":5,"class":6},1]