[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548809":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":45,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Left atrial mapping group in patients without atrial fibrillation",null,"Inclusion criteria:\n\n* Age ≥ 18 years old.\n* Absence of a prior history of atrial fibrillation or flutter.\n* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.\n\nExclusion criteria:\n\n* Presence of thrombus in the left atrial appendage.\n* Complications related to the index procedure.\n* Insufficient quality of the left atrial electroanatomical map.",[13],"Diagnostic Test: Left atrial electroanatomical mapping",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Left atrial electroanatomical mapping","Left atrial electroanatomical mapping (substrate and functional mapping)",[9],[21],{"name":22,"affiliation":5,"role":23},"Andrea Sarkozy, MD, PhD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","0032 02476 3657","Andrea.Sarkozy@uzbrussel.be",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Jette","Brussels Capital","1090","Belgium","BE",{"type":38,"coordinates":39},"Point",[40,41],4.33419,50.87309,{"lat":41,"lon":40},[44],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":23,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Andrea Sarkozy","Clinical Professor","100548809","characterization-of-left-atrial-substrate-in-patients-with-ventricular-arrhythmias-100548809",false,"NCT06425822","Characterization of Left Atrial Substrate in Patients With Ventricular Arrhythmias","CLASS-VA","Inclusion Criteria:\n\n* Absence of a prior history of atrial fibrillation or flutter.\n* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.\n\nExclusion criteria:\n\n* Presence of thrombus in the left atrial appendage.\n* Complications related to the index procedure.\n* Insufficient quality of the left atrial electroanatomical map.","ALL","18 Years",{"count":58,"type":59},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to analyze the characteristics of left atrial electroanatomical maps in patients without a history of atrial fibrillation but with a high clinical risk of developing it, as indicated by the presence of structural heart disease or a CHA2DS2-VASc score ≥ 2 points. The study cohort will be compared to a historical cohort of patients with diagnosed atrial fibrillation in a propensity-matched fashion.\n\nThe main questions it aims to answer are:\n\n* Are the left atrial electroanatomical changes a consequence or a precursor to the development of atrial fibrillation?\n* Are the left atrial electroanatomical findings different between patients with atrial fibrillation and those at high risk of developing it?\n* What is the prognostic impact of left atrial pathologic changes in patients without diagnosed atrial fibrillation in terms of cardiovascular outcomes?",[63],"Atrial Remodeling","2024-05-21",{"date":66,"type":67},"2024-05-22","ACTUAL",{"date":69,"type":67},"2023-11-08",{"date":71,"type":59},"2027-10-31",{"name":5,"class":6},1]