[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589308":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":26,"responsibleParty":45,"collaborators":26,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":26,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":26,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":73,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":26},{"fullName":5,"class":6},"University of California, Irvine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"test: support group with intelligent chatbot","EXPERIMENTAL","When participants post to their support groups, the intelligent chatbot will detect relevant post types and generate responses which will be posted back to them and their group, if no human responds to the post within about 10 seconds. The intelligent chatbot will also post a daily discussion topic.",[13],"Behavioral: online quit-smoking support group with intelligent chatbot",{"label":15,"type":16,"description":17,"interventionNames":18},"control: support group with unintelligent bot","ACTIVE_COMPARATOR","The unintelligent chatbot will not respond to participants' posts; it will merely post a daily discussion topic.",[19],"Behavioral: online quit-smoking support group with unintelligent bot",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","online quit-smoking support group with intelligent chatbot","In the intervention arm (N=60), each quit-smoking peer support group will be connected to an intelligent chatbot running on a secure local server as a trained LLM (large language model). This chatbot will monitor all posts in the group and seek to comprehend these posts using the training it has been provided. If a group member makes a post and no one responds with about 10 seconds, the chatbot will respond using one of its 25 response libraries created from knowledge bases, which contain over 1k responses in total. In effect, the intelligent chatbot will function as an additional member of the GroupMe support group, but a member that only responds if no human does so.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"online quit-smoking support group with unintelligent bot","In the control arm (N=60), the support groups will be connected to our original automated message-posting bot running on our secure local server. This automated message-posting bot will lack the response capabilities of the intelligent chatbot; it will not respond to posts if no human group member does but, instead, remain silent. However, it will post the same daily discussion topic, and at the same time of day, as the intelligent chatbot.",[15],[32],{"name":33,"affiliation":5,"role":34},"Cornelia A. Pechmann, PhD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Cornelia A Pechmann, PhD","CONTACT","3108920619","cpechman@uci.edu",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Ian G. Harris, PhD","9498248842","harris@ics.uci.edu",{"type":34,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Cornelia Pechmann","Professor","100589308","chatbot-for-online-support-groups-to-treat-tobacco-addiction-100589308",false,"NCT06952725","Chatbot for Online Support Groups to Treat Tobacco Addiction","Intelligent Chatbot for Online Support Groups to Treat Tobacco Addiction","Inclusion Criteria:\n\n* Cigarette smokers (can also use e-cigarettes)\n* Ages 18-75 years\n* English speaking\n* Smart phone with unlimited data\n* 100 cigarettes lifetime\n* Prepared to quit smoking within 10 days of study start\n* Active text and email\n* Use of social media or group messaging\n* Home address provided\n* Contact information for a collateral provided\n* Setup of a GroupMe account for study\n\nExclusion Criteria:\n\n* No NRT health contraindications\n* 5+ cigarettes per day\n* Not an illicit drug user\n* Not a daily marijuana\u002Fcannabis user",true,"ALL","18 Years","75 Years",{"count":60,"type":61},120,"ESTIMATED","INTERVENTIONAL",[64],"NA","Investigators will conduct a pilot RCT to test the efficacy of an intelligent chatbot to aid small, private, quit-smoking peer support groups. Participants will be randomized to an intervention arm (chatbot-enhanced support group), or a control arm (support group only). In the intervention arm (N=60), each support group will be connected to an intelligent chatbot running on a secure local server as a trained LLM (large language model). The intelligent chatbot will function as an additional member of the GroupMe support group, but a member that only responds if no human does so. In the control arm (N=60), the support groups will be connected to an automated message-posting bot running on a secure local server. This automated message-posting bot will lack the response capabilities of the intelligent chatbot. But both the intelligent chatbot and the automated message-posting bot will post a pre-written daily discussion topic to encourage participants to discuss issues known to facilitate tobacco cessation or group bonding.",[67,68],"Tobacco Dependence","Tobacco Use Disorder",[70,71,72],"tobacco use addiction","online support group","chatbot","NOT_YET_RECRUITING","2026-05-20",{"date":76,"type":77},"2026-05-22","ACTUAL",{"date":79,"type":61},"2026-12-01",{"date":81,"type":61},"2028-06-01",{"name":5,"class":6}]