[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632935":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":10,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":25,"enrollmentInfo":26,"targetDuration":10,"studyType":29,"phases":10,"briefSummary":30,"conditions":31,"keywords":35,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Neonates with Suspected Congenital Heart Disease",null,"Neonates aged 0 to 28 days admitted to the Neonatal Intensive Care Unit (NICU) presenting with clinical signs (such as cyanosis, heart murmur, or respiratory distress), abnormal pulse oximetry, abnormal antenatal ultrasound findings, or X-ray findings suggestive of congenital heart disease. Participants in this cohort will undergo standard digital chest radiography within 24 hours of clinical suspicion and a confirmatory transthoracic echocardiography within 72 hours.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kerolos Samir Seed Gerges","Resident at Pediatric Department, Assiut University","100632935","chest-x-rays-for-early-detection-of-congenital-heart-disease-in-newborns-100632935",false,"NCT07520149","Chest X-Rays for Early Detection of Congenital Heart Disease in Newborns","Evaluation of Chest X-Ray Findings in Early Detection of Congenital Heart Disease in Neonates","Inclusion Criteria:\n\n* Neonates aged 0-28 days admitted to the NICU with X-ray findings suspecting CHD during the study period.\n* Neonates presenting with clinical signs suggestive of congenital heart disease, including: cyanosis (central or peripheral), heart murmur detected on auscultation, tachypnea, or respiratory distress.\n* Neonates with abnormal pulse oximetry findings (oxygen saturation \\\u003C95% in room air).\n* Neonates with abnormal antenatal ultrasound findings suggesting cardiac anomalies.\n\nExclusion Criteria:\n\n* Infants aged more than 28 days.\n* Infants with no clinical or radiological evidence of CHD.","ALL","0 Days","28 Days",{"count":27,"type":28},60,"ESTIMATED","OBSERVATIONAL","Congenital heart disease (CHD) is a common condition affecting newborns that can be serious if not caught early. While echocardiograms are the best way to diagnose CHD, they are not always immediately available. Chest X-rays are widely available and are often the first test used when a newborn has breathing problems, a heart murmur, or a bluish skin tint.\n\nThe purpose of this study is to determine how accurate standard chest X-rays are at finding congenital heart disease in newborns.\n\nResearchers will observe 60 newborns (up to 28 days old) admitted to the Neonatal Intensive Care Unit (NICU) who have signs or symptoms that suggest they might have a heart problem. Each baby in the study will receive a standard chest X-ray within 24 hours of their clinical presentation. Within 72 hours, they will also receive an echocardiogram, which is the standard, definitive test used to confirm if there is a heart defect.\n\nBy comparing the initial chest X-ray results to the final echocardiogram results, researchers hope to figure out exactly which X-ray patterns are best at predicting specific heart diseases. This could help doctors make faster decisions about treating newborns, potentially reducing delays in diagnosis and improving care.",[32,33,34],"Congenital Heart Disease","Chest X-ray for Clinical Evaluation","Neonates",[32,36,34,37,38],"Chest X-Ray","Echocardiography","Chest Radiography","NOT_YET_RECRUITING","2026-04-03",{"date":42,"type":43},"2026-04-09","ACTUAL",{"date":45,"type":28},"2026-05",{"date":47,"type":28},"2027-06",{"name":5,"class":6}]