[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100463750":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":36,"centralContacts":41,"locations":51,"responsibleParty":71,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":10,"studyType":92,"phases":10,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"transgender men",null,"People whose sex assigned at birth is female but whose self-identified gender is male.",[13],"Drug: GAHT for transgender men",{"label":15,"type":10,"description":16,"interventionNames":17},"transgender women","People whose sex assigned at birth is male but whose self-identified gender is female.",[18],"Drug: GAHT for transgender women",{"label":20,"type":10,"description":21,"interventionNames":10},"Healthy cisgender people","People whose sex assigned at birth corresponds with their self-identified gender.",[23,30],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","GAHT for transgender men","Testosterone undecanoate",[9],[29],"Testosterone",{"type":24,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"GAHT for transgender women","Estradiol and antiandrogens (Spironolactone or Cyproterone acetate)",[15],[35],"Feminizing drugs",[37],{"name":38,"affiliation":39,"role":40},"Tianpei Hong, PhD., M.D.","Department of Endocrinology and Metabolism, Peking University Third Hospital","PRINCIPAL_INVESTIGATOR",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":10,"email":46},"Ye Liu, PhD., M.D.","CONTACT","+86-10-82265025","yeliumed@bjmu.edu.cn",{"name":48,"role":44,"phone":49,"phoneExt":10,"email":50},"Tianpei Hong, M.D.","+86-10-82266918","tpho66@bjmu.edu.cn",[52],{"facility":5,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"RECRUITING","Beijing","Beijing Municipality","100191","China","CN",{"type":60,"coordinates":61},"Point",[62,63],116.39723,39.9075,{"lat":63,"lon":62},[66,69],{"name":67,"role":44,"phone":68,"phoneExt":10,"email":50},"Tianpei Hong, Pro.","8601082265025",{"name":70,"role":44,"phone":68,"phoneExt":10,"email":46},"Ye Liu, Dr.",{"type":40,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Hong Tianpei","Professor",[75],{"name":76,"class":6},"Tsinghua University","100463750","china-gender-affirming-hormone-therapy-study-100463750",false,"NCT05318755","China Gender-affirming Hormone Therapy Study","China Gender-affirming Hormone Therapy Study in Transgender Men and Women","CGAHT","Inclusion Criteria:\n\n* Transgender men and women\n* Meet criteria of Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) for gender dysphoria\n* Aged between 18 to 40 years\n* People desire to start the GAHT\n* No previous history of gender-affirming interventions\n* Having full ability to make informed consent\n* Dextromanual\n\nExclusion Criteria:\n\n* Disorders of sex development\n* Who has fertility demand but have not made fertility preservation\n* With contradictions of GAHT\n* Comorbid diseases are not under control\n* Alcohol or drug abuse\n* Hormonal and chromosomal disorders\n* History of gender affirming surgery\n* Current psychiatric disorders\n* History of brain trauma or neurological pathologies\n* Current use of medications with psychotropic effects within two weeks (antipsychotic or antiepileptic agents, lithium, benzodiazepines or opioid analgesics)\n* Claustrophobia\n* Implanted metal and medical devices (pacemakers, ceramic teeth, etc.),\n* Tattoos or eyebrow tattooing (heavy metal dye)",true,"ALL","18 Years","40 Years",{"count":90,"type":91},240,"ESTIMATED","OBSERVATIONAL","Data about transgender medical care, especially the gender-affirming hormone therapy (GAHT) is extremely insufficient in China. Few evidence exists in the physical and psychological effects of the hormonal treatment in Chinese transgender population. CGAHT is designed to describe the social and mental condition of transgender people who are seeking for formal GAHT, and to investigate the physical and psychological effects of GAHT on this population in China.",[95,96],"Transgender","Gender Incongruence",[98,99],"Transgender Persons","Gender-affirming Hormone Therapy","2024-11-05",{"date":102,"type":103},"2024-11-07","ACTUAL",{"date":105,"type":103},"2022-04-16",{"date":107,"type":91},"2028-12-31",{"name":5,"class":6},1]